D81.7
BillableMajor histocompatibility complex class II deficiency
Major histocompatibility complex class II deficiency
Coding Notes
Includes
Conditions included under this code
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
Excludes 2
Conditions not included here, but the patient may have both
- •autoimmune disease (systemic) NOSM35.9
- •certain conditions originating in the perinatal periodP00-P96
- •complications of pregnancy, childbirth and the puerperiumO9A)O00
- •congenital malformations, deformations and chromosomal abnormalitiesQ00-Q99
- •endocrine, nutritional and metabolic diseasesE00-E88
- •human immunodeficiency virus [HIV] diseaseB20
- •injury, poisoning and certain other consequences of external causesS00-T88
- •neoplasmsC00-D49
- •symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedR00-R94
Related Codes(9)
D81.0Severe combined immunodeficiency with reticular dysgenesis
D81.1Severe combined immunodeficiency w low T- and B-cell numbers
D81.2Severe combined immunodef w low or normal B-cell numbers
D81.3Adenosine deaminase [ADA] deficiency
D81.4Nezelof's syndrome
D81.5Purine nucleoside phosphorylase [PNP] deficiency
D81.6Major histocompatibility complex class I deficiency
D81.8Other combined immunodeficiencies
D81.9Combined immunodeficiency, unspecified
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(65)
SNOMED CT
- Bare lymphocyte syndrome type 2191002000
- Bare lymphocyte syndrome type II191002000
- Immunodeficiency by defective expression of major histocompatibility complex class II191002000
- MHC (major histocompatibility complex) class II deficiency191002000
- Major histocompatibility complex class II deficiency191002000
- Immunodeficiency by defective expression of major histocompatibility complex class II due to regulatory factor X associated protein mutation1351501003
- MHC (major histocompatibility complex) class II deficiency due to RFXAP mutation1351501003
- Major histocompatibility complex class II deficiency due to RFXAP mutation1351501003
- Immunodeficiency by defective expression of major histocompatibility complex class II due to class II major histocompatibility complex transactivator mutation1351502005
- MHC (major histocompatibility complex) class II deficiency due to CIITA mutation1351502005
- Major histocompatibility complex class II deficiency due to CIITA mutation1351502005
- Immunodeficiency by defective expression of major histocompatibility complex class II due to regulatory factor X associated ankyrin containing protein mutation1351503000
- MHC (major histocompatibility complex) class II deficiency due to RFXANK mutation1351503000
- Major histocompatibility complex class II deficiency due to RFXANK mutation1351503000
- Immunodeficiency by defective expression of major histocompatibility complex class II due to regulatory factor X5 mutation1351504006
- MHC (major histocompatibility complex) class II deficiency due to RFX5 mutation1351504006
- Major histocompatibility complex class II deficiency due to RFX5 mutation1351504006
UMLS
- BLS Type IIC2931418
- BLS type IIC2931418
- BLS, TYPE IIC2931418
- Bare Lymphocyte Syndrome Type 2C2931418
- Bare Lymphocyte Syndrome, Type IIC2931418
- Bare lymphocyte syndrome 2C2931418
- Bare lymphocyte syndrome type 2C2931418
- Bare lymphocyte syndrome type IIC2931418
- Immunodeficiency by Defective Expression of MHC Class IIC2931418
- Immunodeficiency by defective expression of major histocompatibility complex class IIC2931418
- Immunodeficiency by defective expression of major histocompatibility complex class II (disorder)C2931418
- MHC (major histocompatibility complex) class II deficiencyC2931418
- Major histocompatibility complex class II deficiencyC2931418
- SCID due to absence of class II HLA antigensC2931418
- SCID, HLA CLASS II-NEGATIVEC2931418
- SCID, HLA Class 2-NegativeC2931418
- SCID, HLA Class II-NegativeC2931418
- SCID, HLA class 2-negativeC2931418
- SCID, HLA class II-negativeC2931418
- SEVERE COMBINED IMMUNODEFICIENCY, HLA CLASS II-NEGATIVEC2931418
- Severe combined immunodeficiency, HLA class II-negativeC2931418
- Severe combined immunodeficiency, HLA class ii-negativeC2931418
Clinical Terms
- Bare lymphocyte syndrome type II
- Immunodeficiency by defective expression of major histocompatibility complex class II due to class II major histocompatibility complex transactivator mutation
- Bare Lymphocyte Syndrome Type 2
- SCID, HLA Class II-Negative
- MHC (major histocompatibility complex) class II deficiency due to RFXAP mutation
- Major histocompatibility complex class II deficiency due to RFXAP mutation
- SCID, HLA Class 2-Negative
- BLS, TYPE II
- SCID due to absence of class II HLA antigens
- Immunodeficiency by defective expression of major histocompatibility complex class II due to regulatory factor X associated protein mutation
- Immunodeficiency by defective expression of major histocompatibility complex class II due to regulatory factor X5 mutation
- Severe combined immunodeficiency, HLA class II-negative
- Immunodeficiency by defective expression of major histocompatibility complex class II due to regulatory factor X associated ankyrin containing protein mutation
- MHC (major histocompatibility complex) class II deficiency due to RFX5 mutation
- BLS type II
- Bare lymphocyte syndrome 2
- Immunodeficiency by Defective Expression of MHC Class II
- Immunodeficiency by defective expression of major histocompatibility complex class II (disorder)
- MHC (major histocompatibility complex) class II deficiency due to CIITA mutation
- Major histocompatibility complex class II deficiency due to RFXANK mutation
- Major histocompatibility complex class II deficiency due to RFX5 mutation
- Immunodeficiency by defective expression of major histocompatibility complex class II
- MHC (major histocompatibility complex) class II deficiency due to RFXANK mutation
- Major histocompatibility complex class II deficiency due to CIITA mutation
- MHC (major histocompatibility complex) class II deficiency
- Bare Lymphocyte Syndrome, Type II
Frequently Asked Questions
What is the ICD-10 code for major histocompatibility complex class ii deficiency?
The ICD-10-CM code for major histocompatibility complex class ii deficiency is D81.7. The full clinical description is "Major histocompatibility complex class II deficiency". D81.7 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code D81.7 mean?
ICD-10-CM code D81.7 represents “Major histocompatibility complex class II deficiency”. It is classified under Chapter 3: Diseases of the Blood and Blood-Forming Organs and is a billable/specific code that can be used on a claim.
Is D81.7 a billable code?
Yes, D81.7 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is D81.7 in?
D81.7 is in Chapter 3: Diseases of the Blood and Blood-Forming Organs (codes D50-D89).
What codes cannot be used with D81.7?
D81.7 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease (systemic) NOS (M35.9); functional disorders of polymorphonuclear neutrophils (D71); human immunodeficiency virus [HIV] disease (B20); and 1 more.
What SNOMED CT codes does D81.7 map to?
D81.7 maps to 5 SNOMED CT concepts: 191002000, 1351502005, 1351503000, 1351501003, 1351504006. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for D81.7?
D81.7 is linked to 1 UMLS Concept Unique Identifier: C2931418. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does D81.7 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like major histocompatibility complex class ii deficiency affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of D81.7?
D81.7 maps to the ICD-11 code: 4A01.12 (Major histocompatibility complex class II deficiency).
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.