D81.9

Billable

Combined immunodeficiency, unspecified

Combined immunodeficiency, unspecified

Status

Billable / Specific

Block

D80-D89

Parent Code

D81

ICD-11 Mapping

1 equivalent

Coding Notes

Inclusion Terms

Alternative clinical terms for this condition

  • Severe combined immunodeficiency disorder [SCID] NOS

Includes

Conditions included under this code

  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Excludes 1

Codes that cannot be used together with this code (mutual exclusion)

Excludes 2

Conditions not included here, but the patient may have both

Related Codes(9)
D81.0

Severe combined immunodeficiency with reticular dysgenesis

BillableD81.1

Severe combined immunodeficiency w low T- and B-cell numbers

BillableD81.2

Severe combined immunodef w low or normal B-cell numbers

BillableD81.3

Adenosine deaminase [ADA] deficiency

D81.4

Nezelof's syndrome

BillableD81.5

Purine nucleoside phosphorylase [PNP] deficiency

BillableD81.6

Major histocompatibility complex class I deficiency

BillableD81.7

Major histocompatibility complex class II deficiency

BillableD81.8

Other combined immunodeficiencies

ICD-11 Equivalents(1)

ICD-11 Equivalents

View full mapping

Corresponding ICD-11 codes from the WHO crosswalk mapping

4A01.1ZCombined immunodeficiencies, unspecifiedequivalentPrimary
Also Known As / Clinical Terms(101)

SNOMED CT

UMLS

Clinical Terms

  • Severe combined immunodeficiency, microcephaly, growth retardation, sensitivity to ionising radiation syndrome
  • TRIANGLE (TPPII-related immunodeficiency, autoimmunity, neurodevelopmental delay, impaired glycolysis, lysosomal expansion) disease
  • Severe combined immunodeficiency, microcephaly, growth retardation, sensitivity to ionizing radiation syndrome
  • Combined immunodeficiency with granulomatosis
  • Combined immunodeficiency disease (disorder)
  • Achondroplasia-Swiss type agammaglobulinemia syndrome
  • SCID - severe combined immunodeficiency
  • combined immunodeficiency syndrome
  • Benign combined immunodeficiency
  • Combined immunodeficiency due to RAG 1/2 (recombination activating gene 1/2) deficiency
  • Severe combined immunodeficiency disorder [SCID] NOS
  • Obstruction of visceral vein
  • Autoimmune hemolytic anemia, autoimmune thrombocytopenia, primary immunodeficiency syndrome
  • VODI syndrome
  • Evans syndrome associated with primary immunodeficiency
  • Hepatic sinusoidal obstruction syndrome
  • VODI (veno-occlusive disease, immunodeficiency) syndrome
  • Severe combined immunodeficiency with maternofetal engraftment
  • Autoimmune haemolytic anaemia, autoimmune thrombocytopenia, primary immunodeficiency syndrome
  • TPPII-related immunodeficiency, autoimmunity and neurodevelopmental delay with impaired glycolysis and lysosomal expansion disease
  • Congenital atrophy of optic nerve
  • Hepatic veno-occlusive disease
  • Hepatic veno-occlusive disease with immunodeficiency syndrome
  • Achondroplasia, severe combined immunodeficiency syndrome
  • Severe combined immunodeficiency
  • Severe combined immunodeficiency with low T- and B-cell numbers
  • Short-limb skeletal dysplasia with severe combined immunodeficiency
  • TPPII (tripeptidyl-peptidase II) deficiency
  • Achondroplasia-Swiss type agammaglobulinaemia syndrome
  • Combined immunodeficiency disease
  • Cernunnos-XLF deficiency
  • Severe combined immunodeficiency with maternofoetal engraftment
  • combined immunity deficiency
  • Combined immunodeficiency due to RAG 1/2 deficiency
  • Congenital Combined Immunodeficiency
  • NHEJ1 (non-homologous end joining factor) syndrome
  • Severe combined immunodeficiency due to Cernunnos protein deficiency
  • Autosomal recessive severe combined immunodeficiency disease
  • Veno-occlusive disease of the liver
  • Autosomal recessive SCID (severe combined immunodeficiency disease)
  • Immunodeficiency, short limb dwarfism syndrome
  • Tripeptidyl-peptidase II deficiency
  • Severe combined immunodeficiency disease
  • Congenital optic atrophy
  • Roifman Chitayat syndrome
  • Combined T-cell and B-cell immunodeficiency
  • Combined immunodeficiency with faciooculoskeletal anomalies syndrome
Frequently Asked Questions
What is the ICD-10 code for combined immunodeficiency, unspecified?

The ICD-10-CM code for combined immunodeficiency, unspecified is D81.9. The full clinical description is "Combined immunodeficiency, unspecified". D81.9 is a billable/specific code that can be used on insurance claims and medical billing.

What does ICD-10 code D81.9 mean?

ICD-10-CM code D81.9 represents “Combined immunodeficiency, unspecified”. It is classified under Chapter 3: Diseases of the Blood and Blood-Forming Organs and is a billable/specific code that can be used on a claim.

Is D81.9 a billable code?

Yes, D81.9 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.

What chapter is D81.9 in?

D81.9 is in Chapter 3: Diseases of the Blood and Blood-Forming Organs (codes D50-D89).

What codes cannot be used with D81.9?

D81.9 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease (systemic) NOS (M35.9); functional disorders of polymorphonuclear neutrophils (D71); human immunodeficiency virus [HIV] disease (B20); and 1 more.

What SNOMED CT codes does D81.9 map to?

D81.9 maps to 15 SNOMED CT concepts: 789777007, 1222681008, 362993009, 234572005, 720853005, and 10 more. SNOMED CT is a clinical terminology used in electronic health records.

What are the UMLS CUIs for D81.9?

D81.9 is linked to 2 UMLS Concept Unique Identifiers: C2711630, C2873846. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.

How does D81.9 relate to ICF functioning codes?

ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like combined immunodeficiency, unspecified affect a person's functioning: body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.

What is the ICD-11 equivalent of D81.9?

D81.9 maps to the ICD-11 code: 4A01.1Z (Combined immunodeficiencies, unspecified).

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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.