M35.9
BillableSystemic involvement of connective tissue, unspecified
Systemic involvement of connective tissue, unspecified
Coding Notes
Inclusion Terms
Alternative clinical terms for this condition
- Autoimmune disease (systemic) NOS
- Collagen (vascular) disease NOS
Includes
Conditions included under this code
- autoimmune disease NOS
- collagen (vascular) disease NOS
- systemic autoimmune disease
- systemic collagen (vascular) disease
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
- autoimmune disease, single organ or single cell-type -code to relevant condition category
- •reactive perforating collagenosisL87.1
Excludes 2
Conditions not included here, but the patient may have both
- •arthropathic psoriasisL40.5
- •certain conditions originating in the perinatal periodP04-P96
- •certain infectious and parasitic diseasesA00-B99
- •compartment syndrome (traumatic)A-)T79
- •complications of pregnancy, childbirth and the puerperiumO9A)O00
- •congenital malformations, deformations, and chromosomal abnormalitiesQ00-Q99
- •endocrine, nutritional and metabolic diseasesE00-E88
- •injury, poisoning and certain other consequences of external causesS00-T88
- •neoplasmsC00-D49
- •symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedR00-R94
Related Codes(9)
M35.0Sjogren syndrome
M35.1Other overlap syndromes
M35.2Behcet's disease
M35.3Polymyalgia rheumatica
M35.4Diffuse (eosinophilic) fasciitis
M35.5Multifocal fibrosclerosis
M35.6Relapsing panniculitis [Weber-Christian]
M35.7Hypermobility syndrome
M35.8Other specified systemic involvement of connective tissue
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(251)
SNOMED CT
- Autoimmune pancytopenia183005
- Neuromyositis31384009
- PM - Polymyositis31384009
- Polymyositis31384009
- Pericarditis co-occurrent and due to collagen vascular disease58474006
- Pericarditis secondary to collagen vascular disease58474006
- Immune neutropenia65623009
- Metabolic disease of collagen73873008
- Collagen disease81573002
- Collagen disorder81573002
- Diffuse disease of connective tissue81573002
- Autoimmune disease85828009
- Autoimmune disorder85828009
- Absent salivary secretion87715008
- Aptyalia87715008
- Aptyalism87715008
- Asialia87715008
- Clinical xerostomia87715008
- Dry mouth87715008
- Xerostomia87715008
- Autoimmune diseases affecting skin95329006
- Autoimmune skin disease95329006
- Neutropenia associated with autoimmune disease111585004
- Autoimmune leucopenia123777002
- Autoimmune leukopenia123777002
- Neuropathy in vasculitis and connective tissue disease193177003
- Polyneuropathy in collagen vascular disease193177003
- Opsoclonus-myoclonus syndrome230350000
- Acquired poikiloderma238839007
- Collagen and elastic tissue disorders affecting skin238846003
- Polymyositis associated with autoimmune disease239899000
- Paroxysmal digital cyanosis266261006
- Raynaud phenomenon266261006
- Raynaud's phenomenon266261006
- Overlap syndrome276657008
- Secondary Raynaud phenomenon356198000
- Secondary Raynaud's phenomenon356198000
- Autoimmune connective tissue disorder362992004
- Congenital connective tissue disorder363039000
- Connective tissue hereditary disorder363045008
- Inherited disorder of connective tissue363045008
- Connective tissue disease overlap syndrome398021003
- MCTD - Mixed connective tissue disease398049005
- Mixed collagen vascular disease398049005
- Mixed connective tissue disease398049005
- Sharp syndrome398049005
- Sharp's syndrome398049005
- Necrotising vasculitis secondary to connective tissue disease402657003
- Necrotizing vasculitis secondary to connective tissue disease402657003
- Poikiloderma due to connective tissue disease403408001
- Dilated cardiomyopathy with connective tissue disorder413994008
- Conjunctivitis associated with autoimmune skin disorder417492002
- Disseminated eosinophilic collagen disease423486005
- Interstitial lung disease due to collagen vascular disease427123006
- Autoimmune sensorineural hearing loss428470000
- Lung disorder due to autoimmune disorder432066002
- Autoimmune inflammation of skeletal muscle443899007
- Autoimmune myositis443899007
- Cerebral small vessel disease443929000
- Small vessel cerebrovascular disease443929000
- PANDAS - Paediatric autoimmune neuropsychiatric disorder associated with streptococcal infection446682003
- PANDAS - Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection446682003
- Paediatric autoimmune neuropsychiatric disorder associated with streptococcal infection446682003
- Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection446682003
- Acquired sensorineural hearing loss609125008
- Associated pulmonary arterial hypertension697902002
- Pulmonary arterial hypertension associated with connective tissue disease697903007
- Idiopathic inflammatory myopathy702380008
- Idiopathic inflammatory myositis702380008
- Autoimmune xerostomia707297005
- Xerostomia due to autoimmune disease707297005
- Interstitial lung disease due to connective tissue disease711379004
- Autoimmune necrotising myopathy715863001
- Autoimmune necrotizing myopathy715863001
- Immune mediated necrotising myopathy715863001
- Immune mediated necrotizing myopathy715863001
- Non-infective ulceration of small intestine722534001
- Polyneuropathy co-occurrent and due to systemic connective tissue disorder724998006
- Polyneuropathy with systemic connective tissue disorder724998006
- Photodermatitis co-occurrent and due to autoimmune disease737249005
- RVCL - retinal vasculopathy cerebral leucoencephalopathy783787000
- RVCL - retinal vasculopathy cerebral leukoencephalopathy783787000
- RVCL-S - retinal vasculopathy, cerebral leucoencephalopathy, systemic manifestations783787000
- RVCL-S - retinal vasculopathy, cerebral leukoencephalopathy, systemic manifestations783787000
- Retinal vasculopathy with cerebral leucoencephalopathy and systemic manifestations783787000
- Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations783787000
- Autoimmune opsoclonus myoclonus838323002
- Autoimmune optic neuropathy838324008
- Autoimmune ganglionopathy838330008
- Cardiomyopathy due to connective tissue disease860837007
- Myocarditis due to autoimmune disease871640001
- Myocarditis in autoimmune disease871640001
- Fetal disorder due to maternal autoimmune disease1003466007
- Foetal disorder due to maternal autoimmune disease1003466007
- Chronic tubulo-interstitial nephritis due to connective tissue disorder1144909003
- Chronic tubulointerstitial nephritis due to connective tissue disorder1144909003
- Autoimmune esophagitis1197684002
- Autoimmune oesophagitis1197684002
- Esophagitis due to autoimmune disease1197684002
- Oesophagitis due to autoimmune disease1197684002
- Non-infectious enteritis due to autoimmune disease1197728007
- Noninfectious enteritis due to autoimmune disease1197728007
- Non-infectious ulceration of small intestine due to autoimmune disease1201779005
- Raynaud phenomenon due to autoimmune disease1208849004
- Autoimmune disorder of autonomic nerve1259077008
- Autoimmune disorder of autonomic nervous system1259090001
- Autoimmune neuropathy of autonomic nervous system1259090001
- Disorder of connective tissue co-occurrent and due to systemic disease300161000119106
- Disorder of connective tissue co-occurrent and due to systemic involvement300161000119106
- Lung disease due to connective tissue disorder146081000119104
UMLS
- Autoimmune disease (systemic) NOSC2895206
- Multi-Organ Autoimmune DiseaseC2895206
- Multiorgan Autoimmune DiseaseC2895206
- Systemic Autoimmune DiseaseC2895206
- systemic autoimmune diseaseC2895206
- Collagen (vascular) disease NOSC0262428
- Collagen-vascular diseaseC0262428
- collagen (vascular) disease NOSC0262428
- collagen disease vascularC0262428
- collagen diseases vascularC0262428
- collagen vascular diseaseC0262428
- collagen vascular diseasesC0262428
- collagen-vascular diseaseC0262428
- vascular collagen diseaseC0262428
- vascular disease collagenC0262428
- Systemic Involvement of Connective Tissue, UnspecifiedC0477583
- Systemic connective tissue disorders (M30-M36)C0477583
- Systemic involvement of connective tissue, unspecifiedC0477583
Clinical Terms
- Autoimmune disorder of autonomic nervous system
- Connective tissue disease overlap syndrome
- Fetal disorder due to maternal autoimmune disease
- collagen-vascular disease
- Esophagitis due to autoimmune disease
- Necrotising vasculitis secondary to connective tissue disease
- Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection
- Systemic connective tissue disorders (M30-M36)
- Photodermatitis co-occurrent and due to autoimmune disease
- Cerebral small vessel disease
- Autoimmune leukopenia
- Non-infective ulceration of small intestine
- Aptyalia
- Chronic tubulointerstitial nephritis due to connective tissue disorder
- Cardiomyopathy due to connective tissue disease
- Myocarditis due to autoimmune disease
- Autoimmune connective tissue disorder
- Lung disorder due to autoimmune disorder
- Autoimmune disease (systemic) NOS
- Collagen disorder
- Disseminated eosinophilic collagen disease
- Paroxysmal digital cyanosis
- Raynaud's phenomenon
- Xerostomia
- PM - Polymyositis
- Idiopathic inflammatory myopathy
- Collagen disease
- Mixed collagen vascular disease
- Autoimmune necrotizing myopathy
- Interstitial lung disease due to collagen vascular disease
- Opsoclonus-myoclonus syndrome
- Disorder of connective tissue co-occurrent and due to systemic disease
- Polyneuropathy co-occurrent and due to systemic connective tissue disorder
- Disorder of connective tissue co-occurrent and due to systemic involvement
- RVCL - retinal vasculopathy cerebral leukoencephalopathy
- Immune neutropenia
- Polyneuropathy with systemic connective tissue disorder
- Raynaud phenomenon due to autoimmune disease
- Conjunctivitis associated with autoimmune skin disorder
- PANDAS - Paediatric autoimmune neuropsychiatric disorder associated with streptococcal infection
- Autoimmune opsoclonus myoclonus
- Pericarditis secondary to collagen vascular disease
- Diffuse disease of connective tissue
- Secondary Raynaud phenomenon
- Collagen and elastic tissue disorders affecting skin
- vascular collagen disease
- Systemic Autoimmune Disease
- Autoimmune disorder
- Autoimmune leucopenia
- Metabolic disease of collagen
- Secondary Raynaud's phenomenon
- Small vessel cerebrovascular disease
- Neutropenia associated with autoimmune disease
- PANDAS - Pediatric autoimmune neuropsychiatric disorder associated with streptococcal infection
- Aptyalism
- Poikiloderma due to connective tissue disease
- Interstitial lung disease due to connective tissue disease
- Autoimmune necrotising myopathy
- Lung disease due to connective tissue disorder
- collagen (vascular) disease NOS
- Asialia
- collagen vascular disease
- Raynaud phenomenon
- Pulmonary arterial hypertension associated with connective tissue disease
- Polymyositis
- Oesophagitis due to autoimmune disease
- collagen diseases vascular
- Xerostomia due to autoimmune disease
- Autoimmune myositis
- Connective tissue hereditary disorder
- Neuropathy in vasculitis and connective tissue disease
- Autoimmune sensorineural hearing loss
- Sharp syndrome
- Autoimmune neuropathy of autonomic nervous system
- Congenital connective tissue disorder
- Autoimmune disease
- Inherited disorder of connective tissue
- RVCL - retinal vasculopathy cerebral leucoencephalopathy
- collagen disease vascular
- Autoimmune disorder of autonomic nerve
- Pericarditis co-occurrent and due to collagen vascular disease
- Autoimmune skin disease
- Autoimmune xerostomia
- Autoimmune optic neuropathy
- Necrotizing vasculitis secondary to connective tissue disease
- Non-infectious enteritis due to autoimmune disease
- vascular disease collagen
- Myocarditis in autoimmune disease
- Retinal vasculopathy with cerebral leucoencephalopathy and systemic manifestations
- Acquired sensorineural hearing loss
- Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations
- Dilated cardiomyopathy with connective tissue disorder
- Chronic tubulo-interstitial nephritis due to connective tissue disorder
- Multiorgan Autoimmune Disease
- Autoimmune inflammation of skeletal muscle
- Autoimmune pancytopenia
- Immune mediated necrotizing myopathy
- Noninfectious enteritis due to autoimmune disease
- Absent salivary secretion
- RVCL-S - retinal vasculopathy, cerebral leukoencephalopathy, systemic manifestations
- Multi-Organ Autoimmune Disease
- Non-infectious ulceration of small intestine due to autoimmune disease
- Sharp's syndrome
- Associated pulmonary arterial hypertension
- Idiopathic inflammatory myositis
- Immune mediated necrotising myopathy
- Autoimmune oesophagitis
- Autoimmune esophagitis
- Clinical xerostomia
- Polyneuropathy in collagen vascular disease
- Autoimmune ganglionopathy
- RVCL-S - retinal vasculopathy, cerebral leucoencephalopathy, systemic manifestations
- Overlap syndrome
- Paediatric autoimmune neuropsychiatric disorder associated with streptococcal infection
- Mixed connective tissue disease
- collagen vascular diseases
- Foetal disorder due to maternal autoimmune disease
- Autoimmune diseases affecting skin
- MCTD - Mixed connective tissue disease
- Dry mouth
- Polymyositis associated with autoimmune disease
- Acquired poikiloderma
- Neuromyositis
Frequently Asked Questions
What is the ICD-10 code for systemic involvement of connective tissue, unspecified?
The ICD-10-CM code for systemic involvement of connective tissue, unspecified is M35.9. The full clinical description is "Systemic involvement of connective tissue, unspecified". M35.9 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code M35.9 mean?
ICD-10-CM code M35.9 represents “Systemic involvement of connective tissue, unspecified”. It is classified under Chapter 13: Diseases of the Musculoskeletal System and Connective Tissue and is a billable/specific code that can be used on a claim.
Is M35.9 a billable code?
Yes, M35.9 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is M35.9 in?
M35.9 is in Chapter 13: Diseases of the Musculoskeletal System and Connective Tissue (codes M00-M99).
What codes cannot be used with M35.9?
M35.9 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease, single organ or single cell-type -code to relevant condition category; reactive perforating collagenosis (L87.1).
What SNOMED CT codes does M35.9 map to?
M35.9 maps to 61 SNOMED CT concepts: 87715008, 238839007, 609125008, 697902002, 362992004, and 56 more. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for M35.9?
M35.9 is linked to 3 UMLS Concept Unique Identifiers: C2895206, C0262428, C0477583. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does M35.9 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like systemic involvement of connective tissue, unspecified affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of M35.9?
M35.9 maps to the ICD-11 code: 4A4Z (Nonorgan specific systemic autoimmune disorders, unspecified).
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.