D81.2
BillableSevere combined immunodef w low or normal B-cell numbers
Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
Coding Notes
Includes
Conditions included under this code
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
Excludes 2
Conditions not included here, but the patient may have both
- •autoimmune disease (systemic) NOSM35.9
- •certain conditions originating in the perinatal periodP00-P96
- •complications of pregnancy, childbirth and the puerperiumO9A)O00
- •congenital malformations, deformations and chromosomal abnormalitiesQ00-Q99
- •endocrine, nutritional and metabolic diseasesE00-E88
- •human immunodeficiency virus [HIV] diseaseB20
- •injury, poisoning and certain other consequences of external causesS00-T88
- •neoplasmsC00-D49
- •symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedR00-R94
Related Codes(9)
D81.0Severe combined immunodeficiency with reticular dysgenesis
D81.1Severe combined immunodeficiency w low T- and B-cell numbers
D81.3Adenosine deaminase [ADA] deficiency
D81.4Nezelof's syndrome
D81.5Purine nucleoside phosphorylase [PNP] deficiency
D81.6Major histocompatibility complex class I deficiency
D81.7Major histocompatibility complex class II deficiency
D81.8Other combined immunodeficiencies
D81.9Combined immunodeficiency, unspecified
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(45)
SNOMED CT
- Severe combined immunodeficiency with low or normal B-cell numbers190998001
- SCIDX1 - severe combined immunodeficiency X-linked765145001
- T cell negative B cell positive severe combined immunodeficiency due to gamma chain deficiency765145001
- T-B+ severe combined immunodeficiency due to gamma chain deficiency765145001
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to IL-7Ralpha deficiency1229940001
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to interleukin 7 receptor deficiency1229940001
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to CD45 deficiency1229941002
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to protein tyrosine phosphatase receptor type C deficiency1229941002
- Autosomal recessive T- B+ severe combined immunodeficiency due to CD3D mutation1351209002
- Autosomal recessive T-B+ SCID (T-cell negative, B-cell positive severe combined immunodeficiency) due to CD3D mutation1351209002
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to CD3 delta subunit of T-cell receptor complex mutation1351209002
- Autosomal recessive T- B+ severe combined immunodeficiency due to CD3E mutation1351210007
- Autosomal recessive T-B+ SCID (T-cell negative, B-cell positive severe combined immunodeficiency) due to CD3E mutation1351210007
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to CD3 epsilon subunit of T-cell receptor complex mutation1351210007
- Autosomal recessive T- B+ severe combined immunodeficiency due to CD3Z mutation1351211006
- Autosomal recessive T-B+ SCID (T-cell negative, B-cell positive severe combined immunodeficiency) due to CD3-ZETA mutation1351211006
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to CD3-ZETA mutation1351211006
- Autosomal recessive T- B+ severe combined immunodeficiency due to SLP76 mutation1351212004
- Autosomal recessive T-B+ SCID (T-cell negative, B-cell positive severe combined immunodeficiency) due to SLP76 mutation1351212004
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to SLP76 mutation1351212004
UMLS
- Severe combined immunodef w low or normal B-cell numbersC0451694
- Severe combined immunodeficiency [SCID] with low or normal B-cell numbersC0451694
- Severe combined immunodeficiency with low or normal B-cell numbersC0451694
- Severe combined immunodeficiency with low or normal B-cell numbers (disorder)C0451694
Clinical Terms
- Autosomal recessive T- B+ severe combined immunodeficiency due to SLP76 mutation
- Severe combined immunodeficiency with low or normal B-cell numbers (disorder)
- Autosomal recessive T-B+ SCID (T-cell negative, B-cell positive severe combined immunodeficiency) due to CD3D mutation
- Autosomal recessive T-B+ SCID (T-cell negative, B-cell positive severe combined immunodeficiency) due to CD3E mutation
- Autosomal recessive T- B+ severe combined immunodeficiency due to CD3Z mutation
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to protein tyrosine phosphatase receptor type C deficiency
- Autosomal recessive T- B+ severe combined immunodeficiency due to CD3E mutation
- Autosomal recessive T-B+ SCID (T-cell negative, B-cell positive severe combined immunodeficiency) due to SLP76 mutation
- Severe combined immunodeficiency with low or normal B-cell numbers
- Autosomal recessive T-B+ SCID (T-cell negative, B-cell positive severe combined immunodeficiency) due to CD3-ZETA mutation
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to interleukin 7 receptor deficiency
- SCIDX1 - severe combined immunodeficiency X-linked
- T-B+ severe combined immunodeficiency due to gamma chain deficiency
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to IL-7Ralpha deficiency
- T cell negative B cell positive severe combined immunodeficiency due to gamma chain deficiency
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to SLP76 mutation
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to CD3-ZETA mutation
- Autosomal recessive T- B+ severe combined immunodeficiency due to CD3D mutation
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to CD45 deficiency
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to CD3 epsilon subunit of T-cell receptor complex mutation
- Autosomal recessive T-cell negative, B-cell positive severe combined immunodeficiency due to CD3 delta subunit of T-cell receptor complex mutation
Frequently Asked Questions
What is the ICD-10 code for severe combined immunodef w low or normal b-cell numbers?
The ICD-10-CM code for severe combined immunodef w low or normal b-cell numbers is D81.2. The full clinical description is "Severe combined immunodeficiency [SCID] with low or normal B-cell numbers". D81.2 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code D81.2 mean?
ICD-10-CM code D81.2 represents “Severe combined immunodeficiency [SCID] with low or normal B-cell numbers”. It is classified under Chapter 3: Diseases of the Blood and Blood-Forming Organs and is a billable/specific code that can be used on a claim.
Is D81.2 a billable code?
Yes, D81.2 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is D81.2 in?
D81.2 is in Chapter 3: Diseases of the Blood and Blood-Forming Organs (codes D50-D89).
What codes cannot be used with D81.2?
D81.2 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease (systemic) NOS (M35.9); functional disorders of polymorphonuclear neutrophils (D71); human immunodeficiency virus [HIV] disease (B20); and 1 more.
What SNOMED CT codes does D81.2 map to?
D81.2 maps to 8 SNOMED CT concepts: 1351209002, 1351210007, 1351211006, 1351212004, 1229941002, and 3 more. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for D81.2?
D81.2 is linked to 1 UMLS Concept Unique Identifier: C0451694. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does D81.2 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like severe combined immunodef w low or normal b-cell numbers affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of D81.2?
D81.2 maps to the ICD-11 code: 4A01.10 (Severe combined immunodeficiencies).
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.