AutoICD API

D81.6

Billable

Major histocompatibility complex class I deficiency

Major histocompatibility complex class I deficiency

Status

Billable / Specific

Block

D80-D89

Parent Code

D81

ICD-11 Mapping

1 equivalent

Coding Notes

Inclusion Terms

Alternative clinical terms for this condition

  • Bare lymphocyte syndrome

Includes

Conditions included under this code

  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Excludes 1

Codes that cannot be used together with this code (mutual exclusion)

Excludes 2

Conditions not included here, but the patient may have both

Related Codes(9)
D81.0

Severe combined immunodeficiency with reticular dysgenesis

BillableD81.1

Severe combined immunodeficiency w low T- and B-cell numbers

BillableD81.2

Severe combined immunodef w low or normal B-cell numbers

BillableD81.3

Adenosine deaminase [ADA] deficiency

D81.4

Nezelof's syndrome

BillableD81.5

Purine nucleoside phosphorylase [PNP] deficiency

BillableD81.7

Major histocompatibility complex class II deficiency

BillableD81.8

Other combined immunodeficiencies

D81.9

Combined immunodeficiency, unspecified

Billable
ICD-11 Equivalents(1)

ICD-11 Equivalents

View full mapping

Corresponding ICD-11 codes from the WHO crosswalk mapping

4A01.11Major histocompatibility complex class I deficiencyequivalentPrimary
Also Known As / Clinical Terms(108)

SNOMED CT

UMLS

Clinical Terms

  • Bare lymphocyte syndrome
  • Immunodeficiency by defective expression of human leucocyte antigen class 1 due to TAP binding protein mutation
  • Immunodeficiency by defective expression of major histocompatibility complex class I
  • MHC (major histocompatibility complex) class I deficiency due to B2M mutation
  • Immunodeficiency by defective expression of human leucocyte antigen class 1
  • Immunodeficiency by Defective Expression of MHC Class I
  • Immunodeficiency by defective expression of human leucocyte antigen class 1 due to beta-2-microglobulin mutation
  • Lymphocyte Syndromes, Bare
  • Immunodeficiency by defective expression of human leucocyte antigen class I
  • Bare lymphocyte syndrome type 1
  • Syndromes, Bare Lymphocyte
  • BLS, TYPE I
  • Bare Lymphocyte Syndromes
  • HLA class I deficiency
  • Major histocompatibility complex class I deficiency due to B2M mutation
  • Immunodeficiency by defective expression of human leukocyte antigen class 1 due to TAP binding protein mutation
  • Immunodeficiency by defective expression of human leukocyte antigen class I
  • Major histocompatibility complex class I deficiency due to TAP1 mutation
  • Bare lymphocyte syndrome type I
  • Immunodeficiency by defective expression of major histocompatibility complex class I due to transporter 1, ATP binding cassette subfamily B member mutation
  • MHC (major histocompatibility complex) class I deficiency
  • HLA CLASS I DEFICIENCY, 1
  • MHC1D1
  • Syndrome, Bare Lymphocyte
  • Immunodeficiency by defective expression of human leukocyte antigen class 1
  • MHC (major histocompatibility complex) class I deficiency due to TAP1 mutation
  • Immunodeficiency by defective expression of major histocompatibility complex class I due to beta-2-microglobulin mutation
  • Immunodeficiency by defective expression of human leukocyte antigen class 1 due to transporter 2, ATP binding cassette subfamily B member mutation
  • MHC (major histocompatibility complex) class I deficiency due to TAPBP mutation
  • MHC CLASS I DEFICIENCY 1
  • Immunodeficiency by defective expression of major histocompatibility complex class I due to TAP binding protein mutation
  • Immunodeficiency by defective expression of HLA (human leukocyte antigen) class 1
  • Immunodeficiency by defective expression of HLA (human leucocyte antigen) class 1
  • Major histocompatibility complex class I deficiency due to TAP2 mutation
  • Bare Lymphocyte Syndrome, Type I
  • Severe combined immunodeficiency due to absent class II human leukocyte antigens
  • Immunodeficiency by defective expression of major histocompatibility complex class I (disorder)
  • MHC (major histocompatibility complex) class I deficiency due to TAP2 mutation
  • Immunodeficiency by defective expression of human leukocyte antigen class 1 due to transporter 1, ATP binding cassette subfamily B member mutation
  • Immunodeficiency by defective expression of human leucocyte antigen class 1 due to transporter 1, ATP binding cassette subfamily B member mutation
  • Major histocompatibility complex class I deficiency due to TAPBP mutation
  • Immunodeficiency by defective expression of human leucocyte antigen class 1 due to transporter 2, ATP binding cassette subfamily B member mutation
  • Immunodeficiency by defective expression of major histocompatibility complex class I due to transporter 2, ATP binding cassette subfamily B member mutation
  • Lymphocyte Syndrome, Bare
  • Immunodeficiency by defective expression of human leukocyte antigen class 1 due to beta-2-microglobulin mutation
Frequently Asked Questions
What is the ICD-10 code for major histocompatibility complex class i deficiency?

The ICD-10-CM code for major histocompatibility complex class i deficiency is D81.6. The full clinical description is "Major histocompatibility complex class I deficiency". D81.6 is a billable/specific code that can be used on insurance claims and medical billing.

What does ICD-10 code D81.6 mean?

ICD-10-CM code D81.6 represents “Major histocompatibility complex class I deficiency”. It is classified under Chapter 3: Diseases of the Blood and Blood-Forming Organs and is a billable/specific code that can be used on a claim.

Is D81.6 a billable code?

Yes, D81.6 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.

What chapter is D81.6 in?

D81.6 is in Chapter 3: Diseases of the Blood and Blood-Forming Organs (codes D50-D89).

What codes cannot be used with D81.6?

D81.6 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease (systemic) NOS (M35.9); functional disorders of polymorphonuclear neutrophils (D71); human immunodeficiency virus [HIV] disease (B20); and 1 more.

What SNOMED CT codes does D81.6 map to?

D81.6 maps to 5 SNOMED CT concepts: 725136003, 1351356002, 1351351007, 1351354004, 1351355003. SNOMED CT is a clinical terminology used in electronic health records.

What are the UMLS CUIs for D81.6?

D81.6 is linked to 2 UMLS Concept Unique Identifiers: C1858266, C0242583. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.

How does D81.6 relate to ICF functioning codes?

ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like major histocompatibility complex class i deficiency affect a person's functioning: body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.

What is the ICD-11 equivalent of D81.6?

D81.6 maps to the ICD-11 code: 4A01.11 (Major histocompatibility complex class I deficiency).

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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.