D89.839
BillableCytokine release syndrome, grade unspecified
Cytokine release syndrome, grade unspecified
Coding Notes
Includes
Conditions included under this code
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
Excludes 2
Conditions not included here, but the patient may have both
- •autoimmune disease (systemic) NOSM35.9
- •certain conditions originating in the perinatal periodP00-P96
- •complications of pregnancy, childbirth and the puerperiumO9A)O00
- •congenital malformations, deformations and chromosomal abnormalitiesQ00-Q99
- •endocrine, nutritional and metabolic diseasesE00-E88
- •human immunodeficiency virus [HIV] diseaseB20
- •injury, poisoning and certain other consequences of external causesS00-T88
- •neoplasmsC00-D49
- •symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedR00-R94
- •transplant failure and rejectionT86
Code First
The underlying condition must be sequenced before this code
Use Additional Code
Additional codes that should follow this code
Related Codes(5)
Also Known As / Clinical Terms(23)
SNOMED CT
- Immune system complication of procedure363142008
- CRS - cytokine release syndrome710027002
- Cytokine release syndrome710027002
- Cytokine-associated toxicity710027002
- Acute intoxication1149334009
- Stoned1149334009
- CAR T (chimeric antigen receptor T) cell therapy-associated CRS (cytokine release syndrome)1230290005
- CAR-T (chimeric antigen receptor T-cell) therapy associated cytokine release syndrome1230290005
- Chimeric antigen receptor T-cell immunotherapy-associated cytokine release syndrome1230290005
- Chimeric antigen receptor-T cell therapy-associated cytokine release syndrome1230290005
- Cytokine release syndrome due to chimeric antigen receptor T-cell immunotherapy1230290005
Clinical Terms
- Cytokine release syndrome due to chimeric antigen receptor T-cell immunotherapy
- Cytokine-associated toxicity
- CAR-T (chimeric antigen receptor T-cell) therapy associated cytokine release syndrome
- CAR T (chimeric antigen receptor T) cell therapy-associated CRS (cytokine release syndrome)
- Chimeric antigen receptor T-cell immunotherapy-associated cytokine release syndrome
- Cytokine release syndrome
- Immune system complication of procedure
- Stoned
- CRS - cytokine release syndrome
- Chimeric antigen receptor-T cell therapy-associated cytokine release syndrome
- Acute intoxication
Frequently Asked Questions
What is the ICD-10 code for cytokine release syndrome, grade unspecified?
The ICD-10-CM code for cytokine release syndrome, grade unspecified is D89.839. The full clinical description is "Cytokine release syndrome, grade unspecified". D89.839 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code D89.839 mean?
ICD-10-CM code D89.839 represents “Cytokine release syndrome, grade unspecified”. It is classified under Chapter 3: Diseases of the Blood and Blood-Forming Organs and is a billable/specific code that can be used on a claim.
Is D89.839 a billable code?
Yes, D89.839 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is D89.839 in?
D89.839 is in Chapter 3: Diseases of the Blood and Blood-Forming Organs (codes D50-D89).
What codes cannot be used with D89.839?
D89.839 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease (systemic) NOS (M35.9); functional disorders of polymorphonuclear neutrophils (D71); human immunodeficiency virus [HIV] disease (B20); and 2 more.
Are additional codes required with D89.839?
Yes, when using D89.839, also report: adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5).
What SNOMED CT codes does D89.839 map to?
D89.839 maps to 4 SNOMED CT concepts: 1149334009, 1230290005, 710027002, 363142008. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for D89.839?
D89.839 is linked to 1 UMLS Concept Unique Identifier: C5384658. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does D89.839 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like cytokine release syndrome, grade unspecified affect a person's functioning: body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of D89.839?
There is no direct ICD-11 mapping available for D89.839 in the WHO crosswalk tables. This may mean the concept is classified differently in ICD-11. Use the ICD-10 to ICD-11 converter to search for related codes.
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.