D89.3
BillableImmune reconstitution syndrome
Immune reconstitution syndrome
Coding Notes
Inclusion Terms
Alternative clinical terms for this condition
- Immune reconstitution inflammatory syndrome [IRIS]
Includes
Conditions included under this code
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
Excludes 2
Conditions not included here, but the patient may have both
- •autoimmune disease (systemic) NOSM35.9
- •certain conditions originating in the perinatal periodP00-P96
- •complications of pregnancy, childbirth and the puerperiumO9A)O00
- •congenital malformations, deformations and chromosomal abnormalitiesQ00-Q99
- •endocrine, nutritional and metabolic diseasesE00-E88
- •human immunodeficiency virus [HIV] diseaseB20
- •injury, poisoning and certain other consequences of external causesS00-T88
- •neoplasmsC00-D49
- •symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedR00-R94
- •transplant failure and rejectionT86
Use Additional Code
Additional codes that should follow this code
Related Codes(6)
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(40)
SNOMED CT
- Immune reconstitution reaction425706005
- Disorder of immune reconstitution425835006
- Evidence of immune reconstitution425857004
- Engraftment reaction426144000
- Immune reconstitution inflammatory syndrome426202004
- Immune reconstitution syndrome426202004
- Engraftment syndrome426768001
- Immune reconstitution finding427096007
UMLS
- Immune Reconstitution DiseaseC1619738
- Immune Reconstitution Inflammatory SyndromeC1619738
- Immune Reconstitution SyndromeC1619738
- Immune Reconstitution SyndromesC1619738
- Immune Restoration DiseaseC1619738
- Immune Restoration DiseasesC1619738
- Immune Restoration SyndromeC1619738
- Immune reconstitution inflammatory syndromeC1619738
- Immune reconstitution inflammatory syndrome (disorder)C1619738
- Immune reconstitution syndromeC1619738
- Immune restoration diseaseC1619738
- Reconstitution Disease, ImmuneC1619738
- Reconstitution Syndrome, ImmuneC1619738
- Restoration Syndrome, ImmuneC1619738
- Immune reconstitution inflammatory syndrome [IRIS]C2976853
Clinical Terms
- Immune Reconstitution Inflammatory Syndrome
- Immune reconstitution reaction
- Disorder of immune reconstitution
- Engraftment syndrome
- Restoration Syndrome, Immune
- Immune reconstitution finding
- Engraftment reaction
- Reconstitution Syndrome, Immune
- Immune reconstitution inflammatory syndrome (disorder)
- Immune Reconstitution Disease
- Immune reconstitution inflammatory syndrome [IRIS]
- Immune Restoration Disease
- Immune Restoration Syndrome
- Evidence of immune reconstitution
- Immune Restoration Diseases
- Immune Reconstitution Syndromes
- Reconstitution Disease, Immune
Frequently Asked Questions
What is the ICD-10 code for immune reconstitution syndrome?
The ICD-10-CM code for immune reconstitution syndrome is D89.3. The full clinical description is "Immune reconstitution syndrome". D89.3 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code D89.3 mean?
ICD-10-CM code D89.3 represents “Immune reconstitution syndrome”. It is classified under Chapter 3: Diseases of the Blood and Blood-Forming Organs and is a billable/specific code that can be used on a claim.
Is D89.3 a billable code?
Yes, D89.3 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is D89.3 in?
D89.3 is in Chapter 3: Diseases of the Blood and Blood-Forming Organs (codes D50-D89).
What codes cannot be used with D89.3?
D89.3 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease (systemic) NOS (M35.9); functional disorders of polymorphonuclear neutrophils (D71); human immunodeficiency virus [HIV] disease (B20); and 2 more.
Are additional codes required with D89.3?
Yes, when using D89.3, also report: adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).
What SNOMED CT codes does D89.3 map to?
D89.3 maps to 7 SNOMED CT concepts: 425835006, 426144000, 426768001, 425857004, 427096007, and 2 more. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for D89.3?
D89.3 is linked to 2 UMLS Concept Unique Identifiers: C1619738, C2976853. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does D89.3 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like immune reconstitution syndrome affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of D89.3?
D89.3 maps to the ICD-11 code: 4B23 (Immune reconstitution inflammatory syndrome).
Automate ICD-10 Coding With AI
Send clinical text to the AutoICD API and get back structured ICD-10 codes with confidence scores. Integrates into any EHR or billing system in minutes.
Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.