A81.2
BillableProgressive multifocal leukoencephalopathy
Progressive multifocal leukoencephalopathy
Coding Notes
Inclusion Terms
Alternative clinical terms for this condition
- Multifocal leukoencephalopathy NOS
Includes
Conditions included under this code
- diseases generally recognized as communicable or transmissible
- diseases of the central nervous system caused by prions
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
- certain localized infections - see body system-related chapters
- •postpolio syndromeG14
- •sequelae of poliomyelitisB91
- •sequelae of viral encephalitisB94.1
Excludes 2
Conditions not included here, but the patient may have both
Use Additional Code
Additional codes that should follow this code
- •code to identify resistance to antimicrobial drugsZ16
- code, if applicable, to identify:
- •dementia with anxiety, A4, B4, C4)F02.84, F02, F02, F02
- •dementia with behavioral disturbance, A1-, B1-, C1-)F02.81, F02, F02, F02
- •dementia with mood disturbance, A3, B3, C3)F02.83, F02, F02, F02
- •dementia with psychotic disturbance, A2, B2, C2)F02.82, F02, F02, F02
- •dementia without behavioral disturbance, A0, B0, C0)F02.80, F02, F02, F02
- •mild neurocognitive disorder due to known physiological conditionF06.7
Related Codes(4)
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(107)
SNOMED CT
- Multifocal leucoencephalopathy22255007
- Multifocal leukoencephalopathy22255007
- PML - Progressive multifocal leucoencephalopathy22255007
- PML - Progressive multifocal leukoencephalopathy22255007
- PMLE - Progressive multifocal leucoencephalopathy22255007
- PMLE - Progressive multifocal leukoencephalopathy22255007
- Progressive multifocal leucoencephalopathy22255007
- Progressive multifocal leukoencephalopathy22255007
- Cerebral degeneration due to progressive multifocal leucoencephalopathy192819000
- Cerebral degeneration due to progressive multifocal leukoencephalopathy192819000
- Progressive multifocal leucoencephalopathy with AIDS (acquired immunodeficiency syndrome)420554003
- Progressive multifocal leucoencephalopathy with acquired immunodeficiency syndrome420554003
- Progressive multifocal leukoencephalopathy with AIDS (acquired immunodeficiency syndrome)420554003
- Progressive multifocal leukoencephalopathy with acquired immunodeficiency syndrome420554003
- Central nervous system demyelinating disease with AIDS (acquired immunodeficiency syndrome)420718004
- Central nervous system demyelinating disease with acquired immunodeficiency syndrome420718004
- Encephalopathy with AIDS (acquired immunodeficiency syndrome)421827003
- Encephalopathy with acquired immunodeficiency syndrome421827003
- Disease caused by JC polyomavirus431257006
- LBSL - Leucoencephalopathy with brainstem and spinal cord involvement with lactate elevation703537008
- LBSL - Leukoencephalopathy with brainstem and spinal cord involvement with lactate elevation703537008
- Leucoencephalopathy with brainstem and spinal cord involvement and lactate elevation703537008
- Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation703537008
- Progressive multifocal leucoencephalopathy co-occurrent with human immunodeficiency virus infection713487008
- Progressive multifocal leukoencephalopathy co-occurrent with human immunodeficiency virus infection713487008
- Demyelinating disease of central nervous system co-occurrent with human immunodeficiency virus infection713543002
- White matter disorder caused by infection722601005
- Dementia co-occurrent and due to progressive multifocal leucoencephalopathy733193001
- Dementia co-occurrent and due to progressive multifocal leukoencephalopathy733193001
- Dementia with progressive multifocal leucoencephalopathy733193001
- Dementia with progressive multifocal leukoencephalopathy733193001
UMLS
- ENCEPH JC POLYOMAVIRUSC0023524
- Encephalitis, JC PolyomavirusC0023524
- Encephalopathies, JC PolyomavirusC0023524
- Encephalopathy, JC PolyomavirusC0023524
- JC POLYOMAVIRUS ENCEPHC0023524
- JC Polyomavirus EncephalitisC0023524
- JC Polyomavirus EncephalopathyC0023524
- LEUKOENCEPH PROGRESSIVE MULTIFOCALC0023524
- Leukoencephalopathies, Progressive MultifocalC0023524
- Leukoencephalopathy, Progressive MultifocalC0023524
- Multifocal Leukoencephalopathies, ProgressiveC0023524
- Multifocal Leukoencephalopathy, ProgressiveC0023524
- Multifocal leucoencephalopathyC0023524
- Multifocal leukoencephalopathyC0023524
- Multifocal leukoencephalopathy NOSC0023524
- PMLC0023524
- PML - Progressive multifocal leucoencephalopathyC0023524
- PML - Progressive multifocal leukoencephalopathyC0023524
- PMLE - Progressive multifocal leucoencephalopathyC0023524
- PMLE - Progressive multifocal leukoencephalopathyC0023524
- PROGRESSIVE MULTIFOCAL LEUKOENCEPHC0023524
- Progressive Multifocal LeukoencephalopathiesC0023524
- Progressive Multifocal LeukoencephalopathyC0023524
- Progressive multifocal leucoencephalopathyC0023524
- Progressive multifocal leukoencephalopathyC0023524
- Progressive multifocal leukoencephalopathy (disorder)C0023524
- multifocal leukoencephalopathyC0023524
- pmlC0023524
- progressive multifocal leukoencephalopathyC0023524
Clinical Terms
- JC Polyomavirus Encephalitis
- LEUKOENCEPH PROGRESSIVE MULTIFOCAL
- Dementia co-occurrent and due to progressive multifocal leucoencephalopathy
- Demyelinating disease of central nervous system co-occurrent with human immunodeficiency virus infection
- JC POLYOMAVIRUS ENCEPH
- PROGRESSIVE MULTIFOCAL LEUKOENCEPH
- Encephalopathies, JC Polyomavirus
- Dementia with progressive multifocal leukoencephalopathy
- PML - Progressive multifocal leukoencephalopathy
- Cerebral degeneration due to progressive multifocal leukoencephalopathy
- White matter disorder caused by infection
- Disease caused by JC polyomavirus
- Multifocal leukoencephalopathy
- Multifocal leukoencephalopathy NOS
- Multifocal Leukoencephalopathy, Progressive
- Encephalopathy, JC Polyomavirus
- Cerebral degeneration due to progressive multifocal leucoencephalopathy
- PML
- PMLE - Progressive multifocal leucoencephalopathy
- Progressive multifocal leucoencephalopathy
- Encephalopathy with acquired immunodeficiency syndrome
- Progressive multifocal leukoencephalopathy with acquired immunodeficiency syndrome
- Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation
- Multifocal leucoencephalopathy
- Central nervous system demyelinating disease with acquired immunodeficiency syndrome
- LBSL - Leucoencephalopathy with brainstem and spinal cord involvement with lactate elevation
- Encephalopathy with AIDS (acquired immunodeficiency syndrome)
- Leukoencephalopathy, Progressive Multifocal
- Progressive multifocal leucoencephalopathy co-occurrent with human immunodeficiency virus infection
- PML - Progressive multifocal leucoencephalopathy
- Progressive multifocal leukoencephalopathy (disorder)
- Leukoencephalopathies, Progressive Multifocal
- PMLE - Progressive multifocal leukoencephalopathy
- Encephalitis, JC Polyomavirus
- Dementia with progressive multifocal leucoencephalopathy
- Progressive Multifocal Leukoencephalopathies
- ENCEPH JC POLYOMAVIRUS
- Progressive multifocal leukoencephalopathy co-occurrent with human immunodeficiency virus infection
- Progressive multifocal leukoencephalopathy with AIDS (acquired immunodeficiency syndrome)
- JC Polyomavirus Encephalopathy
- LBSL - Leukoencephalopathy with brainstem and spinal cord involvement with lactate elevation
- Central nervous system demyelinating disease with AIDS (acquired immunodeficiency syndrome)
- Progressive multifocal leucoencephalopathy with AIDS (acquired immunodeficiency syndrome)
- Progressive multifocal leucoencephalopathy with acquired immunodeficiency syndrome
- Dementia co-occurrent and due to progressive multifocal leukoencephalopathy
- Multifocal Leukoencephalopathies, Progressive
- Leucoencephalopathy with brainstem and spinal cord involvement and lactate elevation
Frequently Asked Questions
What is the ICD-10 code for progressive multifocal leukoencephalopathy?
The ICD-10-CM code for progressive multifocal leukoencephalopathy is A81.2. The full clinical description is "Progressive multifocal leukoencephalopathy". A81.2 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code A81.2 mean?
ICD-10-CM code A81.2 represents “Progressive multifocal leukoencephalopathy”. It is classified under Chapter 1: Certain Infectious and Parasitic Diseases and is a billable/specific code that can be used on a claim.
Is A81.2 a billable code?
Yes, A81.2 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is A81.2 in?
A81.2 is in Chapter 1: Certain Infectious and Parasitic Diseases (codes A00-B99).
What codes cannot be used with A81.2?
A81.2 has Excludes1 notes indicating codes that cannot be used together with it, including: certain localized infections - see body system-related chapters; postpolio syndrome (G14); sequelae of poliomyelitis (B91); and 1 more.
Are additional codes required with A81.2?
Yes, when using A81.2, also report: resistance to antimicrobial drugs (Z16.-); code, if applicable, to identify:; dementia with anxiety (F02.84, F02.A4, F02.B4, F02.C4); dementia with behavioral disturbance (F02.81-, F02.A1-, F02.B1-, F02.C1-); dementia with mood disturbance (F02.83, F02.A3, F02.B3, F02.C3); dementia with psychotic disturbance (F02.82, F02.A2, F02.B2, F02.C2); dementia without behavioral disturbance (F02.80, F02.A0, F02.B0, F02.C0); mild neurocognitive disorder due to known physiological condition (F06.7-).
What SNOMED CT codes does A81.2 map to?
A81.2 maps to 11 SNOMED CT concepts: 420718004, 192819000, 733193001, 713543002, 431257006, and 6 more. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for A81.2?
A81.2 is linked to 1 UMLS Concept Unique Identifier: C0023524. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does A81.2 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like progressive multifocal leukoencephalopathy affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of A81.2?
A81.2 maps to the ICD-11 code: 8A45.02 (Progressive multifocal leukoencephalopathy).
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.