R65.2
Non-billableSevere sepsis
Severe sepsis
This is a header/category code. For billing purposes, use a more specific child code from the list below.
Coding Notes
Inclusion Terms
Alternative clinical terms for this condition
- Infection with associated acute organ dysfunction
- Sepsis with acute organ dysfunction
- Sepsis with multiple organ dysfunction
- Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction
Excludes 2
Conditions not included here, but the patient may have both
- •abnormal findings on antenatal screening of motherO28
- •certain conditions originating in the perinatal periodP04-P96
- signs and symptoms classified in the body system chapters
- •signs and symptoms of breast,N63, N64.5
Code First
The underlying condition must be sequenced before this code
- underlying infection, such as:
- •infection following a procedureT81.4
- •infections following infusion, transfusion and therapeutic injectionT80.2
- •puerperal sepsisO85
- •sepsis following complete or unspecified spontaneous abortionO03.87
- •sepsis following ectopic and molar pregnancyO08.82
- •sepsis following incomplete spontaneous abortionO03.37
- •sepsis following (induced) termination of pregnancyO04.87
- •sepsis NOSA41.9
Use Additional Code
Additional codes that should follow this code
Child Codes (2)
Related Codes(1)
Related Conditions
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(9)
UMLS
- Infection with associated acute organ dysfunctionC2830467
- Sepsis with Organ DysfunctionC1719672
- Sepsis, SevereC1719672
- Severe SepsisC1719672
- Severe sepsisC1719672
- Severe sepsis NOSC1719672
- Sepsis with acute organ dysfunctionC1719673
- Sepsis with multiple organ dysfunctionC2830468
- Systemic inflammatory response syndrome due to infectious process with acute organ dysfunctionC1719675
Frequently Asked Questions
What is the ICD-10 code for severe sepsis?
The ICD-10-CM code for severe sepsis is R65.2. The full clinical description is "Severe sepsis". R65.2 is a non-billable header code. Use a more specific child code for billing purposes.
What does ICD-10 code R65.2 mean?
ICD-10-CM code R65.2 represents “Severe sepsis”. It is classified under Chapter 18: Symptoms, Signs and Abnormal Clinical and Laboratory Findings and is a non-billable header code. Use a more specific child code for billing purposes.
Is R65.2 a billable code?
No, R65.2 is a non-billable header code. You need to use one of its more specific child codes for billing. There are 2 child codes under R65.2.
What chapter is R65.2 in?
R65.2 is in Chapter 18: Symptoms, Signs and Abnormal Clinical and Laboratory Findings (codes R00-R99).
What are the subcategories under R65.2?
R65.2 has 2 child codes, including: R65.20 (Severe sepsis without septic shock), R65.21 (Severe sepsis with septic shock).
Are additional codes required with R65.2?
Yes, when using R65.2, also report: specific acute organ dysfunction, such as:; acute kidney failure (N17.-); acute respiratory failure (J96.0-); critical illness myopathy (G72.81); critical illness polyneuropathy (G62.81); disseminated intravascular coagulopathy [DIC] (D65); encephalopathy (metabolic) (septic) (G93.41); hepatic failure (K72.0-).
What are the UMLS CUIs for R65.2?
R65.2 is linked to 5 UMLS Concept Unique Identifiers: C2830467, C1719672, C1719673, C2830468, C1719675. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does R65.2 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like severe sepsis affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of R65.2?
R65.2 maps to the ICD-11 code: MG46 (Systemic inflammatory response syndrome of noninfectious origin).
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.