R65.1
Non-billableSIRS of non-infectious origin
Systemic inflammatory response syndrome (SIRS) of non-infectious origin
This is a header/category code. For billing purposes, use a more specific child code from the list below.
Coding Notes
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
- sepsis- code to infection
- •severe sepsisR65.2
Excludes 2
Conditions not included here, but the patient may have both
- •abnormal findings on antenatal screening of motherO28
- •certain conditions originating in the perinatal periodP04-P96
- signs and symptoms classified in the body system chapters
- •signs and symptoms of breast,N63, N64.5
Code First
The underlying condition must be sequenced before this code
- underlying condition, such as:
- •heatstrokeT67.0
- •injury and traumaS00-T88
Child Codes (2)
Related Codes(1)
Related Conditions
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(2)
Frequently Asked Questions
What is the ICD-10 code for sirs of non-infectious origin?
The ICD-10-CM code for sirs of non-infectious origin is R65.1. The full clinical description is "Systemic inflammatory response syndrome (SIRS) of non-infectious origin". R65.1 is a non-billable header code. Use a more specific child code for billing purposes.
What does ICD-10 code R65.1 mean?
ICD-10-CM code R65.1 represents “Systemic inflammatory response syndrome (SIRS) of non-infectious origin”. It is classified under Chapter 18: Symptoms, Signs and Abnormal Clinical and Laboratory Findings and is a non-billable header code. Use a more specific child code for billing purposes.
Is R65.1 a billable code?
No, R65.1 is a non-billable header code. You need to use one of its more specific child codes for billing. There are 2 child codes under R65.1.
What chapter is R65.1 in?
R65.1 is in Chapter 18: Symptoms, Signs and Abnormal Clinical and Laboratory Findings (codes R00-R99).
What codes cannot be used with R65.1?
R65.1 has Excludes1 notes indicating codes that cannot be used together with it, including: sepsis- code to infection; severe sepsis (R65.2).
What are the subcategories under R65.1?
R65.1 has 2 child codes, including: R65.10 (SIRS of non-infectious origin w/o acute organ dysfunction), R65.11 (SIRS of non-infectious origin w acute organ dysfunction).
What are the UMLS CUIs for R65.1?
R65.1 is linked to 1 UMLS Concept Unique Identifier: C2830464. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does R65.1 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like sirs of non-infectious origin affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of R65.1?
R65.1 maps to the ICD-11 code: 1H0Z (Infection, unspecified).
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.