AutoICD API

M35.81

Billable

Multisystem inflammatory syndrome

Multisystem inflammatory syndrome

Status

Billable / Specific

Block

M30-M36

Parent Code

M35.8

Coding Notes

Inclusion Terms

Alternative clinical terms for this condition

  • MIS-A
  • MIS-C
  • Multisystem inflammatory syndrome in adults
  • Multisystem inflammatory syndrome in children
  • Pediatric inflammatory multisystem syndrome
  • PIMS

Includes

Conditions included under this code

  • autoimmune disease NOS
  • collagen (vascular) disease NOS
  • systemic autoimmune disease
  • systemic collagen (vascular) disease

Excludes 1

Codes that cannot be used together with this code (mutual exclusion)

Excludes 2

Conditions not included here, but the patient may have both

Code First

The underlying condition must be sequenced before this code

Use Additional Code

Additional codes that should follow this code

Code Also

A second code may be required; sequencing depends on circumstances

Related Codes(1)
M35.89

Other specified systemic involvement of connective tissue

Billable

Related Conditions

COVID-19
Also Known As / Clinical Terms(52)

SNOMED CT

UMLS

Clinical Terms

  • PIMS-TS - paediatric inflammatory multisystem syndrome temporally associated with COVID-19
  • PIMS - paediatric inflammatory multisystem syndrome
  • MIS-C - multisystem inflammatory syndrome in children
  • Systemic inflammatory response syndrome
  • MIS-C
  • PIMS
  • PIMS-TS - pediatric inflammatory multisystem syndrome temporally associated with COVID-19
  • Pediatric inflammatory multisystem syndrome
  • Multisystem inflammatory syndrome in children
  • Multisystem inflammatory syndrome in adults (disorder)
  • Multi-system inflammatory syndrome in children
  • Paediatric inflammatory multisystem syndrome
  • Adult inflammatory multisystem syndrome temporally associated with COVID-19
  • Multisystem Inflammatory Syndrome in Adults
  • MIS-A - multisystem inflammatory syndrome in adults
  • SIRS - System inflammatory response syndrome
  • MIS-C multisystem inflammatory syndrome in children
  • Pediatric multisystem inflammatory syndrome
  • PIMS - pediatric inflammatory multisystem syndrome
  • MIS-A
  • Paediatric multisystem inflammatory syndrome
Frequently Asked Questions
What is the ICD-10 code for multisystem inflammatory syndrome?

The ICD-10-CM code for multisystem inflammatory syndrome is M35.81. The full clinical description is "Multisystem inflammatory syndrome". M35.81 is a billable/specific code that can be used on insurance claims and medical billing.

What does ICD-10 code M35.81 mean?

ICD-10-CM code M35.81 represents “Multisystem inflammatory syndrome”. It is classified under Chapter 13: Diseases of the Musculoskeletal System and Connective Tissue and is a billable/specific code that can be used on a claim.

Is M35.81 a billable code?

Yes, M35.81 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.

What chapter is M35.81 in?

M35.81 is in Chapter 13: Diseases of the Musculoskeletal System and Connective Tissue (codes M00-M99).

What codes cannot be used with M35.81?

M35.81 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease, single organ or single cell-type -code to relevant condition category; reactive perforating collagenosis (L87.1).

Are additional codes required with M35.81?

Yes, when using M35.81, also report: code, if applicable, for:; exposure to COVID-19 or SARS-CoV-2 infection (Z20.822); personal history of COVID-19 (Z86.16); post COVID-19 condition (U09.9).

What SNOMED CT codes does M35.81 map to?

M35.81 maps to 3 SNOMED CT concepts: 1119306006, 895448002, 238149007. SNOMED CT is a clinical terminology used in electronic health records.

What are the UMLS CUIs for M35.81?

M35.81 is linked to 3 UMLS Concept Unique Identifiers: C5439527, C5389369, C5539184. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.

How does M35.81 relate to ICF functioning codes?

ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like multisystem inflammatory syndrome affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.

What is the ICD-11 equivalent of M35.81?

There is no direct ICD-11 mapping available for M35.81 in the WHO crosswalk tables. This may mean the concept is classified differently in ICD-11. Use the ICD-10 to ICD-11 converter to search for related codes.

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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.