E72.12
BillableMethylenetetrahydrofolate reductase deficiency
Methylenetetrahydrofolate reductase deficiency
Coding Notes
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
- •transitory endocrine and metabolic disorders specific to newbornP70-P74
- •androgen insensitivity syndromeE34.5
- •congenital adrenal hyperplasiaE25.0
- •hemolytic anemias attributable to enzyme disordersD55
- •Marfan syndromeQ87.4
- •5-alpha-reductase deficiencyE29.1
- disorders of:
- •aromatic amino-acid metabolismE70
- •branched-chain amino-acid metabolismE71.0-E71.2
- •fatty-acid metabolismE71.3
- •purine and pyrimidine metabolismE79
- •gout (M1A.-,M10
- •cystinosisE72.04
- •cystinuriaE72.01
- •transcobalamin II deficiencyD51.2
Related Codes(3)
Also Known As / Clinical Terms(24)
SNOMED CT
- Inherited disorder of folate metabolism4702003
- Homocystinuria11282001
- Methylene THF reductase deficiency AND homocystinuria28093001
- Methylene tetrahydrofolate methyltransferase reductase deficiency AND homocystinuria28093001
- 5,10-Methylenetetrahydrofolate reductase deficiency41797007
- Methylenetetrahydrofolate reductase deficiency41797007
- Heterozygous methylenetetrahydrofolate reductase mutation139821000119102
- Homozygous methylenetetrahydrofolate reductase mutation139811000119109
UMLS
Clinical Terms
- 5,10-Methylenetetrahydrofolate reductase deficiency
- Methylene THF reductase deficiency AND homocystinuria
- HOMOCYSTINURIA DUE TO DEFICIENCY OF N(5,10)-METHYLENETETRAHYDROFOLATE REDUCTASE ACTIVITY
- Homozygous methylenetetrahydrofolate reductase mutation
- MTHFR DEFICIENCY
- Heterozygous methylenetetrahydrofolate reductase mutation
- Homocystinuria
- Methylene tetrahydrofolate methyltransferase reductase deficiency AND homocystinuria
- Inherited disorder of folate metabolism
- HOMOCYSTEINURIA DUE TO MTHFR DEFICIENCY
Frequently Asked Questions
What is the ICD-10 code for methylenetetrahydrofolate reductase deficiency?
The ICD-10-CM code for methylenetetrahydrofolate reductase deficiency is E72.12. The full clinical description is "Methylenetetrahydrofolate reductase deficiency". E72.12 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code E72.12 mean?
ICD-10-CM code E72.12 represents “Methylenetetrahydrofolate reductase deficiency”. It is classified under Chapter 4: Endocrine, Nutritional and Metabolic Diseases and is a billable/specific code that can be used on a claim.
Is E72.12 a billable code?
Yes, E72.12 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is E72.12 in?
E72.12 is in Chapter 4: Endocrine, Nutritional and Metabolic Diseases (codes E00-E89).
What codes cannot be used with E72.12?
E72.12 has Excludes1 notes indicating codes that cannot be used together with it, including: transitory endocrine and metabolic disorders specific to newborn (P70-P74); androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); and 12 more.
What SNOMED CT codes does E72.12 map to?
E72.12 maps to 6 SNOMED CT concepts: 41797007, 139821000119102, 11282001, 139811000119109, 4702003, and 1 more. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for E72.12?
E72.12 is linked to 1 UMLS Concept Unique Identifier: C1856061. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does E72.12 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like methylenetetrahydrofolate reductase deficiency affect a person's functioning: body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of E72.12?
There is no direct ICD-11 mapping available for E72.12 in the WHO crosswalk tables. This may mean the concept is classified differently in ICD-11. Use the ICD-10 to ICD-11 converter to search for related codes.
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.