D80.5
BillableImmunodeficiency with increased immunoglobulin M [IgM]
Immunodeficiency with increased immunoglobulin M [IgM]
Coding Notes
Includes
Conditions included under this code
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
Excludes 2
Conditions not included here, but the patient may have both
- •autoimmune disease (systemic) NOSM35.9
- •certain conditions originating in the perinatal periodP00-P96
- •complications of pregnancy, childbirth and the puerperiumO9A)O00
- •congenital malformations, deformations and chromosomal abnormalitiesQ00-Q99
- •endocrine, nutritional and metabolic diseasesE00-E88
- •human immunodeficiency virus [HIV] diseaseB20
- •injury, poisoning and certain other consequences of external causesS00-T88
- •neoplasmsC00-D49
- •symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedR00-R94
Related Codes(9)
D80.0Hereditary hypogammaglobulinemia
D80.1Nonfamilial hypogammaglobulinemia
D80.2Selective deficiency of immunoglobulin A [IgA]
D80.3Selective deficiency of immunoglobulin G [IgG] subclasses
D80.4Selective deficiency of immunoglobulin M [IgM]
D80.6Antibody defic w near-norm immunoglob or w hyperimmunoglob
D80.7Transient hypogammaglobulinemia of infancy
D80.8Other immunodeficiencies with predominantly antibody defects
D80.9Immunodeficiency with predominantly antibody defects, unsp
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(103)
SNOMED CT
- Hyper IgM syndrome82286005
- Hyperimmunoglobulin M syndrome82286005
- Immunodeficiency with IgM hypergammaglobulinaemia82286005
- Immunodeficiency with IgM hypergammaglobulinemia82286005
- Hyper-IgM syndrome due to CD40 ligand deficiency403835002
- Hyper-IgM syndrome due to CD40L deficiency403835002
- Hyper-IgM syndrome type 1403835002
- X-linked hyper-IgM syndrome403835002
- X-linked hyper-immunoglobulin M syndrome403835002
- X-linked with hyper-IgM immunodeficiency403835002
- Autosomal recessive hyper- immunoglobulin M syndrome403836001
- Autosomal recessive hyper-IgM syndrome403836001
- Autosomal recessive hyperimmunoglobulin M syndrome403836001
- CMMR-D (constitutional mismatch repair deficiency) syndrome764946008
- Constitutional mismatch repair deficiency syndrome764946008
- Hyper-IgM syndrome with susceptibility to opportunistic infections783248004
- Hyperimmunoglobulin M syndrome with susceptibility to opportunistic infection783248004
- Hyper-IgM syndrome without susceptibility to opportunistic infections783249007
- Hyperimmunoglobulin M syndrome without susceptibility to opportunistic infection783249007
- Autosomal recessive hyperimmunoglobulin M syndrome due to UNG deficiency1351569004
- Autosomal recessive hyperimmunoglobulin M syndrome due to uracil DNA glycosylase deficiency1351569004
- Hyper-IgM syndrome due to UNG1351569004
- Hyper-IgM syndrome due to uracil N-glycosylase1351569004
- Hyper-IgM syndrome type 51351569004
- Autosomal dominant activation-induced cytidine deaminase deficiency1351570003
- Autosomal dominant hyper IgM syndrome due to AICDA1351570003
- Autosomal dominant hyper-IgM syndrome type 21351570003
- Autosomal dominant hyperimmunoglobulin M syndrome due to AID deficiency1351570003
- Autosomal dominant hyperimmunoglobulin M syndrome due to activation induced cytidine deaminase deficiency1351570003
- Autosomal recessive activation-induced cytidine deaminase deficiency1351572006
- Autosomal recessive hyper IgM syndrome due to AICDA1351572006
- Autosomal recessive hyper-IgM syndrome type 21351572006
- Autosomal recessive hyperimmunoglobulin M syndrome due to AID deficiency1351572006
- Autosomal recessive hyperimmunoglobulin M syndrome due to activation induced cytidine deaminase deficiency1351572006
- Autosomal recessive hyperimmunoglobulin M syndrome due to APRIL deficiency1351573001
- Hyper IgM syndrome due to TNFSF131351573001
- Autosomal recessive hyperimmunoglobulin M syndrome due to CTNNBL1 deficiency1351575008
- Autosomal recessive hyperimmunoglobulin M syndrome due to catenin beta like 1deficiency1351575008
- Hyper IgM syndrome due to CTNNBL11351575008
- Autosomal recessive hyperimmunoglobulin M syndrome due to MSH6 deficiency1351576009
- Autosomal recessive hyperimmunoglobulin M syndrome due to mutS homolog 6 deficiency1351576009
- Autosomal recessive hyperimmunoglobulin M syndrome due to mutator S homolog 6 deficiency1351576009
- Hyper IgM syndrome due to MSH61351576009
- Autosomal recessive hyperimmunoglobulin M syndrome due to INO80 complex ATPase subunit deficiency1351577000
- Autosomal recessive hyperimmunoglobulin M syndrome due to INO80 deficiency1351577000
- Hyper IgM syndrome due to INO801351577000
- Autosomal recessive combined immunodeficiency due to CD40 mutation1362020006
- HIGM3 - hyperimmunoglobulin M syndrome type 31362020006
- Hyper-IgM syndrome due to CD40 deficiency1362020006
- Hyperimmunoglobulin M syndrome type 31362020006
UMLS
Clinical Terms
- Autosomal recessive hyperimmunoglobulin M syndrome due to CTNNBL1 deficiency
- Autosomal recessive hyperimmunoglobulin M syndrome due to UNG deficiency
- Hyper-IgM syndrome due to uracil N-glycosylase
- Hyper IgM syndrome due to INO80
- Hyper-IgM syndrome type 1
- Autosomal recessive hyper- immunoglobulin M syndrome
- Autosomal recessive hyperimmunoglobulin M syndrome due to APRIL deficiency
- Autosomal recessive activation-induced cytidine deaminase deficiency
- Autosomal recessive hyperimmunoglobulin M syndrome
- Autosomal recessive hyperimmunoglobulin M syndrome due to AID deficiency
- Hyper-IgM syndrome due to CD40 deficiency
- Autosomal dominant hyperimmunoglobulin M syndrome due to activation induced cytidine deaminase deficiency
- Immunodeficiency with IgM hypergammaglobulinemia
- Hyper-IgM syndrome due to CD40 ligand deficiency
- Autosomal recessive combined immunodeficiency due to CD40 mutation
- Autosomal dominant activation-induced cytidine deaminase deficiency
- Hyperimmunoglobulin M syndrome with susceptibility to opportunistic infection
- Hyperimmunoglobulin M syndrome without susceptibility to opportunistic infection
- Immunodeficiency with increased immunoglobulin M
- Autosomal dominant hyper-IgM syndrome type 2
- Hyperimmunoglobulin M syndrome
- Autosomal recessive hyperimmunoglobulin M syndrome due to mutator S homolog 6 deficiency
- CMMR-D (constitutional mismatch repair deficiency) syndrome
- Hyper-IgM syndrome due to UNG
- Autosomal recessive hyperimmunoglobulin M syndrome due to uracil DNA glycosylase deficiency
- Hyper-IgM syndrome due to CD40L deficiency
- Constitutional mismatch repair deficiency syndrome
- Autosomal recessive hyperimmunoglobulin M syndrome due to INO80 complex ATPase subunit deficiency
- Hyper-IgM syndrome type 5
- Hyper IgM syndrome due to MSH6
- Autosomal recessive hyperimmunoglobulin M syndrome due to mutS homolog 6 deficiency
- Immunodeficiency with IgM hypergammaglobulinaemia
- X-linked hyper-immunoglobulin M syndrome
- Hyper-IgM syndrome with susceptibility to opportunistic infections
- Autosomal dominant hyper IgM syndrome due to AICDA
- Autosomal recessive hyper-IgM syndrome type 2
- HIGM3 - hyperimmunoglobulin M syndrome type 3
- Autosomal recessive hyperimmunoglobulin M syndrome due to activation induced cytidine deaminase deficiency
- Hyper IgM syndrome due to TNFSF13
- Autosomal dominant hyperimmunoglobulin M syndrome due to AID deficiency
- Hyper-IgM syndrome without susceptibility to opportunistic infections
- Hyperimmunoglobulin M syndrome type 3
- Autosomal recessive hyper-IgM syndrome
- Hyper IgM syndrome
- Autosomal recessive hyperimmunoglobulin M syndrome due to MSH6 deficiency
- X-linked hyper-IgM syndrome
- Autosomal recessive hyperimmunoglobulin M syndrome due to catenin beta like 1deficiency
- Autosomal recessive hyper IgM syndrome due to AICDA
- Autosomal recessive hyperimmunoglobulin M syndrome due to INO80 deficiency
- Hyper IgM syndrome due to CTNNBL1
- X-linked with hyper-IgM immunodeficiency
Frequently Asked Questions
What is the ICD-10 code for immunodeficiency with increased immunoglobulin m [igm]?
The ICD-10-CM code for immunodeficiency with increased immunoglobulin m [igm] is D80.5. The full clinical description is "Immunodeficiency with increased immunoglobulin M [IgM]". D80.5 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code D80.5 mean?
ICD-10-CM code D80.5 represents “Immunodeficiency with increased immunoglobulin M [IgM]”. It is classified under Chapter 3: Diseases of the Blood and Blood-Forming Organs and is a billable/specific code that can be used on a claim.
Is D80.5 a billable code?
Yes, D80.5 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is D80.5 in?
D80.5 is in Chapter 3: Diseases of the Blood and Blood-Forming Organs (codes D50-D89).
What codes cannot be used with D80.5?
D80.5 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease (systemic) NOS (M35.9); functional disorders of polymorphonuclear neutrophils (D71); human immunodeficiency virus [HIV] disease (B20).
What SNOMED CT codes does D80.5 map to?
D80.5 maps to 14 SNOMED CT concepts: 1351570003, 1351572006, 1362020006, 403836001, 1351573001, and 9 more. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for D80.5?
D80.5 is linked to 1 UMLS Concept Unique Identifier: C0740331. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does D80.5 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like immunodeficiency with increased immunoglobulin m [igm] affect a person's functioning: body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of D80.5?
D80.5 maps to the ICD-11 code: 4A01.05 (Immunodeficiencies with severe reduction in serum IgG or IgA with normal or elevated IgM and normal numbers of B-cells).
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.