D57.4
Non-billableSickle-cell thalassemia
Sickle-cell thalassemia
This is a header/category code. For billing purposes, use a more specific child code from the list below.
Coding Notes
Inclusion Terms
Alternative clinical terms for this condition
- Sickle-cell beta thalassemia
- Thalassemia Hb-S disease
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
Excludes 2
Conditions not included here, but the patient may have both
- •autoimmune disease (systemic) NOSM35.9
- •certain conditions originating in the perinatal periodP00-P96
- •complications of pregnancy, childbirth and the puerperiumO9A)O00
- •congenital malformations, deformations and chromosomal abnormalitiesQ00-Q99
- •endocrine, nutritional and metabolic diseasesE00-E88
- •human immunodeficiency virus [HIV] diseaseB20
- •injury, poisoning and certain other consequences of external causesS00-T88
- •neoplasmsC00-D49
- •symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedR00-R94
Use Additional Code
Additional codes that should follow this code
Child Codes (6)
D57.40Sickle-cell thalassemia without crisis
D57.41Sickle-cell thalassemia, unspecified, with crisis
D57.42Sickle-cell thalassemia beta zero without crisis
D57.43Sickle-cell thalassemia beta zero with crisis
D57.44Sickle-cell thalassemia beta plus without crisis
D57.45Sickle-cell thalassemia beta plus with crisis
Related Codes(5)
Also Known As / Clinical Terms(38)
UMLS
- Double heterozygous for Hb S and beta thalassaemiaC0221019
- Double heterozygous for Hb S and beta thalassemiaC0221019
- Haemoglobin S/beta thalassaemiaC0221019
- Hemoglobin S/beta thalassemiaC0221019
- Sickle Beta ThalassemiaC0221019
- Sickle Cell-Beta ThalassemiaC0221019
- Sickle cell-beta-thalassaemiaC0221019
- Sickle cell-beta-thalassemiaC0221019
- Sickle cell-beta-thalassemia (disorder)C0221019
- Thalassaemia with haemoglobin S diseaseC0221019
- Thalassemia Hb-S diseaseC0221019
- Thalassemia with hemoglobin S diseaseC0221019
- Haemoglobin S-F diseaseC2242796
- Hemoglobin S-F diseaseC2242796
- Microdrepanocytic diseaseC2242796
- MicrodrepanocytosisC2242796
- Sickle Cell-ThalassemiaC2242796
- Sickle cell thalassaemiaC2242796
- Sickle cell thalassaemia diseaseC2242796
- Sickle cell thalassemiaC2242796
- Sickle cell thalassemia diseaseC2242796
- Sickle cell-thalassaemia diseaseC2242796
- Sickle cell-thalassemia diseaseC2242796
- Sickle cell-thalassemia disease (disorder)C2242796
- Sickle-cell thalassemiaC2242796
- Sickle-cell thalassemia NOSC2242796
- Thalassaemia sickle cellC2242796
- Thalassaemia-haemoglobin S diseaseC2242796
- Thalassemia sickle cellC2242796
- Thalassemia-hemoglobin S diseaseC2242796
- hemoglobin s thalassemiaC2242796
- sickle cell thalassaemiaC2242796
- sickle cell thalassemiaC2242796
- Sickle cell beta plus thalassaemiaC0857812
- Sickle cell beta plus thalassemiaC0857812
- Sickle cell beta plus thalassemia (disorder)C0857812
- Sickle-cell beta thalassaemiaC0857812
- Sickle-cell beta thalassemiaC0857812
Frequently Asked Questions
What is the ICD-10 code for sickle-cell thalassemia?
The ICD-10-CM code for sickle-cell thalassemia is D57.4. The full clinical description is "Sickle-cell thalassemia". D57.4 is a non-billable header code. Use a more specific child code for billing purposes.
What does ICD-10 code D57.4 mean?
ICD-10-CM code D57.4 represents “Sickle-cell thalassemia”. It is classified under Chapter 3: Diseases of the Blood and Blood-Forming Organs and is a non-billable header code. Use a more specific child code for billing purposes.
Is D57.4 a billable code?
No, D57.4 is a non-billable header code. You need to use one of its more specific child codes for billing. There are 6 child codes under D57.4.
What chapter is D57.4 in?
D57.4 is in Chapter 3: Diseases of the Blood and Blood-Forming Organs (codes D50-D89).
What codes cannot be used with D57.4?
D57.4 has Excludes1 notes indicating codes that cannot be used together with it, including: other hemoglobinopathies (D58.-).
What are the subcategories under D57.4?
D57.4 has 6 child codes, including: D57.40 (Sickle-cell thalassemia without crisis), D57.41 (Sickle-cell thalassemia, unspecified, with crisis), D57.42 (Sickle-cell thalassemia beta zero without crisis), D57.43 (Sickle-cell thalassemia beta zero with crisis), and 2 more.
Are additional codes required with D57.4?
Yes, when using D57.4, also report: any associated fever (R50.81).
What are the UMLS CUIs for D57.4?
D57.4 is linked to 3 UMLS Concept Unique Identifiers: C0221019, C2242796, C0857812. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does D57.4 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like sickle-cell thalassemia affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of D57.4?
There is no direct ICD-11 mapping available for D57.4 in the WHO crosswalk tables. This may mean the concept is classified differently in ICD-11. Use the ICD-10 to ICD-11 converter to search for related codes.
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.