AutoICD API

D89.83

Non-billable

Cytokine release syndrome

Cytokine release syndrome

This is a header/category code. For billing purposes, use a more specific child code from the list below.

Status

Non-billable / Header

Block

D80-D89

Parent Code

D89.8

Child Codes

6

Coding Notes

Includes

Conditions included under this code

  • defects in the complement system
  • immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
  • sarcoidosis

Excludes 1

Codes that cannot be used together with this code (mutual exclusion)

  • autoimmune disease (systemic) NOS (M35.9)
  • functional disorders of polymorphonuclear neutrophils (D71)
  • human immunodeficiency virus [HIV] disease (B20)
  • hyperglobulinemia NOS (R77.1)
  • monoclonal gammopathy (of undetermined significance) (D47.2)

Excludes 2

Conditions not included here, but the patient may have both

  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • transplant failure and rejection (T86.-)

Code First

The underlying condition must be sequenced before this code

  • underlying cause, such as:
  • complications following infusion, transfusion and therapeutic injection (T80.89-)
  • complications of transplanted organs and tissue (T86.-)

Use Additional Code

Additional codes that should follow this code

  • code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5)

Child Codes (6)

D89.831

Cytokine release syndrome, grade 1

BillableD89.832

Cytokine release syndrome, grade 2

BillableD89.833

Cytokine release syndrome, grade 3

BillableD89.834

Cytokine release syndrome, grade 4

BillableD89.835

Cytokine release syndrome, grade 5

BillableD89.839

Cytokine release syndrome, grade unspecified

Billable

Also Known As / Clinical Terms

UMLS

Frequently Asked Questions

What is the ICD-10 code for cytokine release syndrome?

The ICD-10-CM code for cytokine release syndrome is D89.83. The full clinical description is "Cytokine release syndrome". D89.83 is a non-billable header code. Use a more specific child code for billing purposes.

What does ICD-10 code D89.83 mean?

ICD-10-CM code D89.83 represents "Cytokine release syndrome". It is classified under Chapter 3: Diseases of the Blood and Blood-Forming Organs and is a non-billable header code. Use a more specific child code for billing purposes.

Is D89.83 a billable code?

No, D89.83 is a non-billable header code. You need to use one of its more specific child codes for billing. There are 6 child codes under D89.83.

What chapter is D89.83 in?

D89.83 is in Chapter 3: Diseases of the Blood and Blood-Forming Organs (codes D50-D89).

What codes cannot be used with D89.83?

D89.83 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease (systemic) NOS (M35.9); functional disorders of polymorphonuclear neutrophils (D71); human immunodeficiency virus [HIV] disease (B20); and 2 more.

What are the subcategories under D89.83?

D89.83 has 6 child codes, including: D89.831 (Cytokine release syndrome, grade 1), D89.832 (Cytokine release syndrome, grade 2), D89.833 (Cytokine release syndrome, grade 3), D89.834 (Cytokine release syndrome, grade 4), and 2 more.

Are additional codes required with D89.83?

Yes, when using D89.83 you should also code: code for adverse effect, if applicable, to identify immune checkpoint inhibitors and immunostimulant drugs (T45.AX5).

What are the UMLS CUIs for D89.83?

D89.83 is linked to 1 UMLS Concept Unique Identifier: C0948245. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.

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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.