T45
Non-billablePrimarily systemic and hematological agents, NEC
Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified
This is a header/category code. For billing purposes, use a more specific child code from the list below.
Coding Notes
Includes
Conditions included under this code
- adverse effect of correct substance properly administered
- poisoning by overdose of substance
- poisoning by wrong substance given or taken in error
- underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
Excludes 2
Conditions not included here, but the patient may have both
Code First
The underlying condition must be sequenced before this code
- , for adverse effects, the nature of the adverse effect, such as:
- •adverse effect NOST88.7
- •aspirin gastritisK29
- •blood disordersD56-D76
- •contact dermatitisL23-L25
- •dermatitis due to substances taken internallyL27
- •nephropathyN14.0-N14.2
Use Additional Code
Additional codes that should follow this code
7th Character Definitions
- A - initial encounter
- D - subsequent encounter
- S - sequela
Child Codes (11)
T45.0Antiallergic and antiemetic drugs
T45.1Antineoplastic and immunosuppressive drugs
T45.2Poisoning by, adverse effect of and underdosing of vitamins
T45.3Poisoning by, adverse effect of and underdosing of enzymes
T45.4Iron and its compounds
T45.5Anticoagulants and antithrombotic drugs
T45.6Fibrinolysis-affecting drugs
T45.7Anticoagulant antagonists, vitamin K and oth coagulants
T45.8Primarily systemic and hematological agents
T45.9Unsp primarily systemic and hematological agent
T45.AImmune checkpoint inhibitors and immunostimulant drugs
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(2)
Frequently Asked Questions
What is the ICD-10 code for primarily systemic and hematological agents, nec?
The ICD-10-CM code for primarily systemic and hematological agents, nec is T45. The full clinical description is "Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified". T45 is a non-billable header code. Use a more specific child code for billing purposes.
What does ICD-10 code T45 mean?
ICD-10-CM code T45 represents “Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified”. It is classified under Chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes and is a non-billable header code. Use a more specific child code for billing purposes.
Is T45 a billable code?
No, T45 is a non-billable header code. You need to use one of its more specific child codes for billing. There are 11 child codes under T45.
What chapter is T45 in?
T45 is in Chapter 19: Injury, Poisoning and Certain Other Consequences of External Causes (codes S00-T88).
What codes cannot be used with T45?
T45 has Excludes1 notes indicating codes that cannot be used together with it, including: birth trauma (P10-P15); obstetric trauma (O70-O71); toxic reaction to local anesthesia in pregnancy (O29.3-).
What are the subcategories under T45?
T45 has 11 child codes, including: T45.0 (Antiallergic and antiemetic drugs), T45.1 (Antineoplastic and immunosuppressive drugs), T45.2 (Poisoning by, adverse effect of and underdosing of vitamins), T45.3 (Poisoning by, adverse effect of and underdosing of enzymes), and 7 more.
Are additional codes required with T45?
Yes, when using T45, also report: any retained foreign body, if applicable (Z18.-); code(s) to specify:; manifestations of poisoning; underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9); underdosing of medication regimen (Z91.12-, Z91.13-).
What are the UMLS CUIs for T45?
T45 is linked to 1 UMLS Concept Unique Identifier: C2879019. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does T45 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like primarily systemic and hematological agents, nec affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of T45?
T45 maps to the ICD-11 code: NE60 (Harmful effects of drugs, medicaments or biological substances, not elsewhere classified).
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.