G31.81
BillableAlpers disease
Alpers disease
Coding Notes
Inclusion Terms
Alternative clinical terms for this condition
- Grey-matter degeneration
Excludes 2
Conditions not included here, but the patient may have both
- •certain conditions originating in the perinatal periodP04-P96
- •certain infectious and parasitic diseasesA00-B99
- •complications of pregnancy, childbirth and the puerperiumO9A)O00
- •congenital malformations, deformations, and chromosomal abnormalitiesQ00-Q99
- •endocrine, nutritional and metabolic diseasesE00-E88
- •injury, poisoning and certain other consequences of external causesS00-T88
- •neoplasmsC00-D49
- •symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedR00-R94
- •Reye's syndromeG93.7
Use Additional Code
Additional codes that should follow this code
- •code, if applicable, for codes , , to identify:G31.0-G31.83, G31.85-G31.9
- •dementia with anxiety, A4, B4, C4)F02.84, F02, F02, F02
- •dementia with behavioral disturbance, A1-, B1-, C1-)F02.81, F02, F02, F02
- •dementia with mood disturbance, A3, B3, C3)F02.83, F02, F02, F02
- •dementia with psychotic disturbance, A2, B2, C2)F02.82, F02, F02, F02
- •dementia without behavioral disturbance, A0, B0, C0)F02.80, F02, F02, F02
- •mild neurocognitive disorder due to known physiological conditionF06.7
Related Codes(7)
G31.80Leukodystrophy, unspecified
G31.82Leigh's disease
G31.83Neurocognitive disorder with Lewy bodies
G31.84Mild cognitive impairment of uncertain or unknown etiology
G31.85Corticobasal degeneration
G31.86Alexander disease
G31.89Other specified degenerative diseases of nervous system
Also Known As / Clinical Terms(94)
SNOMED CT
- Alper's disease20415001
- Alpers' disease20415001
- Gray matter degeneration20415001
- Grey matter degeneration20415001
- Poliodystrophy20415001
- Progressive neuronal degeneration with liver cirrhosis20415001
- Progressive sclerosing poliodystrophy20415001
- Spongy glioneuronal dystrophy20415001
- Progressive neuronal degeneration of childhood230363006
UMLS
- AHDC0205710
- AHSC0205710
- ALPERS DIFFUSE DEGENERATION OF CEREBRAL GRAY MATTER WITH HEPATIC CIRRHOSISC0205710
- ALPERS DISC0205710
- ALPERS PROGRESSIVE INFANTILE POLIODYSTROPHYC0205710
- ALPERS SYNDROMEC0205710
- ALPERS-HUTTENLOCHER SYNDROMEC0205710
- Alper DiseaseC0205710
- Alper SyndromeC0205710
- Alper's DiseaseC0205710
- Alper's SyndromeC0205710
- Alper's diseaseC0205710
- Alpers Diffuse Degeneration of Cerebral Gray Matter with Hepatic CirrhosisC0205710
- Alpers DiseaseC0205710
- Alpers Huttenlocher DiseaseC0205710
- Alpers Huttenlocher SyndromeC0205710
- Alpers Progressive Infantile PoliodystrophyC0205710
- Alpers SyndromeC0205710
- Alpers diffuse degeneration of cerebral gray matter with hepatic cirrhosisC0205710
- Alpers diseaseC0205710
- Alpers progressive infantile poliodystrophyC0205710
- Alpers syndromeC0205710
- Alpers' DiseaseC0205710
- Alpers' SyndromeC0205710
- Alpers' diseaseC0205710
- Alpers-Huttenlocher SyndromeC0205710
- Alpers-Huttenlocher syndromeC0205710
- Disease, Alpers'C0205710
- Gray matter degenerationC0205710
- Grey matter degenerationC0205710
- Grey-matter degenerationC0205710
- MITOCHONDRIAL DNA DEPLETION SYNDROME 4A (ALPERS TYPE)C0205710
- MTDPS4AC0205710
- NEURONAL DEGENERATION OF CHILDHOOD WITH LIVER DISEASE, PROGRESSIVEC0205710
- Neuronal Degeneration Of Childhood With Liver Disease, ProgressiveC0205710
- PNDCC0205710
- PoliodystrophyC0205710
- Progressive Neuronal Degeneration of Childhood with Liver DiseaseC0205710
- Progressive Sclerosing PoliodystrophiesC0205710
- Progressive Sclerosing PoliodystrophyC0205710
- Progressive neuronal degeneration with liver cirrhosisC0205710
- Progressive sclerosing poliodystrophyC0205710
- Progressive sclerosing poliodystrophy (disorder)C0205710
- Spongy glioneuronal dystrophyC0205710
- Syndrome, AlpersC0205710
- Syndrome, Alpers-HuttenlocherC0205710
- alper diseaseC0205710
- alper syndromeC0205710
- alper's diseaseC0205710
- alpers diseaseC0205710
- alpers syndromeC0205710
- alpers' diseaseC0205710
Clinical Terms
- Alper's Syndrome
- Alpers Diffuse Degeneration of Cerebral Gray Matter with Hepatic Cirrhosis
- Progressive Neuronal Degeneration of Childhood with Liver Disease
- alpers syndrome
- Poliodystrophy
- Syndrome, Alpers
- Progressive neuronal degeneration with liver cirrhosis
- Gray matter degeneration
- NEURONAL DEGENERATION OF CHILDHOOD WITH LIVER DISEASE, PROGRESSIVE
- ALPERS-HUTTENLOCHER SYNDROME
- MTDPS4A
- Alpers Progressive Infantile Poliodystrophy
- PNDC
- alper syndrome
- alper's disease
- MITOCHONDRIAL DNA DEPLETION SYNDROME 4A (ALPERS TYPE)
- Syndrome, Alpers-Huttenlocher
- Progressive sclerosing poliodystrophy
- Grey-matter degeneration
- Spongy glioneuronal dystrophy
- Alpers Huttenlocher Syndrome
- Alpers' disease
- alper disease
- Alpers' Syndrome
- AHD
- ALPERS DIS
- Disease, Alpers'
- Progressive sclerosing poliodystrophy (disorder)
- AHS
- Progressive neuronal degeneration of childhood
- Progressive Sclerosing Poliodystrophies
- Alpers Huttenlocher Disease
- Grey matter degeneration
Frequently Asked Questions
What is the ICD-10 code for alpers disease?
The ICD-10-CM code for alpers disease is G31.81. The full clinical description is "Alpers disease". G31.81 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code G31.81 mean?
ICD-10-CM code G31.81 represents “Alpers disease”. It is classified under Chapter 6: Diseases of the Nervous System and is a billable/specific code that can be used on a claim.
Is G31.81 a billable code?
Yes, G31.81 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is G31.81 in?
G31.81 is in Chapter 6: Diseases of the Nervous System (codes G00-G99).
Are additional codes required with G31.81?
Yes, when using G31.81, also report: code, if applicable, for codes G31.0-G31.83, G31.85-G31.9, to identify:; dementia with anxiety (F02.84, F02.A4, F02.B4, F02.C4); dementia with behavioral disturbance (F02.81-, F02.A1-, F02.B1-, F02.C1-); dementia with mood disturbance (F02.83, F02.A3, F02.B3, F02.C3); dementia with psychotic disturbance (F02.82, F02.A2, F02.B2, F02.C2); dementia without behavioral disturbance (F02.80, F02.A0, F02.B0, F02.C0); mild neurocognitive disorder due to known physiological condition (F06.7-).
What SNOMED CT codes does G31.81 map to?
G31.81 maps to 2 SNOMED CT concepts: 20415001, 230363006. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for G31.81?
G31.81 is linked to 1 UMLS Concept Unique Identifier: C0205710. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does G31.81 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like alpers disease affect a person's functioning: body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of G31.81?
There is no direct ICD-11 mapping available for G31.81 in the WHO crosswalk tables. This may mean the concept is classified differently in ICD-11. Use the ICD-10 to ICD-11 converter to search for related codes.
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.