E16.4
BillableIncreased secretion of gastrin
Increased secretion of gastrin
Coding Notes
Inclusion Terms
Alternative clinical terms for this condition
- Hypergastrinemia
- Hyperplasia of pancreatic endocrine cells with gastrin excess
- Zollinger-Ellison syndrome
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
Related Codes(7)
E16.0Drug-induced hypoglycemia without coma
E16.1Other hypoglycemia
E16.2Hypoglycemia, unspecified
E16.3Increased secretion of glucagon
E16.8Other specified disorders of pancreatic internal secretion
E16.9Disorder of pancreatic internal secretion, unspecified
E16.AHypoglycemia level
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(105)
SNOMED CT
- Hyperplasia of islet alpha cells with gastrin excess1051005
- Familial hypergastrinaemic duodenal ulcer6761005
- Familial hypergastrinemic duodenal ulcer6761005
- Islet cell hyperplasia42681006
- Nesidioblastosis42681006
- Pancreatic endocrine cell hyperplasia42681006
- Abnormality of secretion of gastrin47344007
- Excessive gastrin secretion53132006
- ZE - Zollinger-Ellison syndrome53132006
- Zollinger-Ellison syndrome53132006
- Abnormal hormone secretion53439008
- Disorder of hormone secretion53439008
- Megaloblastic anaemia due to Zollinger-Ellison syndrome54698001
- Megaloblastic anemia due to Zollinger-Ellison syndrome54698001
- Impaired acid inhibition of gastrin release56497004
- G cell tumor302824004
- G cell tumour302824004
- Gastrinoma302824004
- Drug-induced hypergastrinaemia717889000
- Drug-induced hypergastrinemia717889000
- Hypergastrinaemia caused by drug717889000
- Hypergastrinemia caused by drug717889000
- Anastomotic ulcer due to Zollinger-Ellison syndrome717890009
- Gastric ulcer due to Zollinger-Ellison syndrome717891008
- Duodenal ulcer due to Zollinger-Ellison syndrome717892001
- Cancerous ulcer870711002
- Malignant ulcer870711002
- Ulcer due to cancer870711002
- Hypergastrinaemia367641000119101
- Hypergastrinemia367641000119101
- Increased gastrin secretion367641000119101
UMLS
- Excessive gastrin secretionC0043515
- Syndrome Zollinger EllisonC0043515
- Syndrome, Zollinger-EllisonC0043515
- Z-E syndromeC0043515
- ZE - Zollinger-Ellison syndromeC0043515
- Zollinger Ellison SyndromeC0043515
- Zollinger Ellison syndromeC0043515
- Zollinger-Ellison SyndromeC0043515
- Zollinger-Ellison syndromeC0043515
- Zollinger-Ellison syndrome (disorder)C0043515
- ellison syndrome zollingerC0043515
- gastrinoma syndromeC0043515
- syndrome gastrinomaC0043515
- syndrome z-eC0043515
- syndrome zollinger ellisonC0043515
- syndrome zollinger ellisonsC0043515
- syndrome zollinger-ellisonC0043515
- ulcerogenic tumor of the pancreas syndromeC0043515
- z-e syndromeC0043515
- zollinger ellison syndromeC0043515
- zollinger-ellison syndromeC0043515
- HypergastrinaemiaC0232567
- HypergastrinemiaC0232567
- Increased gastrin secretionC0232567
- Increased gastrin secretion (disorder)C0232567
- hypergastrinaemiaC0232567
- hypergastrinemiaC0232567
- Hyperplasia of pancreatic endocrine cells with gastrin excessC2874180
- Increased secretion of gastrinC2874181
Clinical Terms
- Pancreatic endocrine cell hyperplasia
- z-e syndrome
- Hypergastrinemia
- Hypergastrinaemia
- syndrome zollinger ellison
- syndrome gastrinoma
- Impaired acid inhibition of gastrin release
- Megaloblastic anemia due to Zollinger-Ellison syndrome
- Hyperplasia of pancreatic endocrine cells with gastrin excess
- Hypergastrinemia caused by drug
- syndrome z-e
- Increased gastrin secretion
- Drug-induced hypergastrinaemia
- Zollinger-Ellison syndrome (disorder)
- G cell tumour
- Malignant ulcer
- Anastomotic ulcer due to Zollinger-Ellison syndrome
- Ulcer due to cancer
- Excessive gastrin secretion
- Gastric ulcer due to Zollinger-Ellison syndrome
- Nesidioblastosis
- Syndrome, Zollinger-Ellison
- Familial hypergastrinaemic duodenal ulcer
- Islet cell hyperplasia
- Drug-induced hypergastrinemia
- Zollinger-Ellison syndrome
- Increased gastrin secretion (disorder)
- Hypergastrinaemia caused by drug
- Zollinger Ellison syndrome
- syndrome zollinger-ellison
- ulcerogenic tumor of the pancreas syndrome
- ZE - Zollinger-Ellison syndrome
- Abnormality of secretion of gastrin
- syndrome zollinger ellisons
- Duodenal ulcer due to Zollinger-Ellison syndrome
- Hyperplasia of islet alpha cells with gastrin excess
- Abnormal hormone secretion
- G cell tumor
- Megaloblastic anaemia due to Zollinger-Ellison syndrome
- gastrinoma syndrome
- Disorder of hormone secretion
- Familial hypergastrinemic duodenal ulcer
- Gastrinoma
- ellison syndrome zollinger
- Cancerous ulcer
Frequently Asked Questions
What is the ICD-10 code for increased secretion of gastrin?
The ICD-10-CM code for increased secretion of gastrin is E16.4. The full clinical description is "Increased secretion of gastrin". E16.4 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code E16.4 mean?
ICD-10-CM code E16.4 represents “Increased secretion of gastrin”. It is classified under Chapter 4: Endocrine, Nutritional and Metabolic Diseases and is a billable/specific code that can be used on a claim.
Is E16.4 a billable code?
Yes, E16.4 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is E16.4 in?
E16.4 is in Chapter 4: Endocrine, Nutritional and Metabolic Diseases (codes E00-E89).
What codes cannot be used with E16.4?
E16.4 has Excludes1 notes indicating codes that cannot be used together with it, including: transitory endocrine and metabolic disorders specific to newborn (P70-P74).
What SNOMED CT codes does E16.4 map to?
E16.4 maps to 15 SNOMED CT concepts: 53439008, 47344007, 717890009, 870711002, 717889000, and 10 more. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for E16.4?
E16.4 is linked to 4 UMLS Concept Unique Identifiers: C0043515, C0232567, C2874180, C2874181. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does E16.4 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like increased secretion of gastrin affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of E16.4?
E16.4 maps to the ICD-11 code: 5A43.Z (Abnormal secretion of gastrin, unspecified).
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.