D46.4
BillableRefractory anemia, unspecified
Refractory anemia, unspecified
Coding Notes
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
Excludes 2
Conditions not included here, but the patient may have both
Use Additional Code
Additional codes that should follow this code
Related Codes(8)
D46.0Refractory anemia without ring sideroblasts, so stated
D46.1Refractory anemia with ring sideroblasts
D46.2Refractory anemia with excess of blasts [RAEB]
D46.9Myelodysplastic syndrome, unspecified
D46.ARefractory cytopenia with multilineage dysplasia
D46.BRefract cytopenia w multilin dysplasia and ring sideroblasts
D46.CMyelodysplastic syndrome w isolated del(5q) chromsoml abnlt
D46.ZOther myelodysplastic syndromes
ICD-11 Equivalents(1)
ICD-11 Equivalents
View full mappingCorresponding ICD-11 codes from the WHO crosswalk mapping
Also Known As / Clinical Terms(1)
Frequently Asked Questions
What is the ICD-10 code for refractory anemia, unspecified?
The ICD-10-CM code for refractory anemia, unspecified is D46.4. The full clinical description is "Refractory anemia, unspecified". D46.4 is a billable/specific code that can be used on insurance claims and medical billing.
What does ICD-10 code D46.4 mean?
ICD-10-CM code D46.4 represents “Refractory anemia, unspecified”. It is classified under Chapter 2: Neoplasms and is a billable/specific code that can be used on a claim.
Is D46.4 a billable code?
Yes, D46.4 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is D46.4 in?
D46.4 is in Chapter 2: Neoplasms (codes C00-D49).
What codes cannot be used with D46.4?
D46.4 has Excludes1 notes indicating codes that cannot be used together with it, including: neoplasms of unspecified behavior (D49.-).
Are additional codes required with D46.4?
Yes, when using D46.4, also report: adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).
What are the UMLS CUIs for D46.4?
D46.4 is linked to 1 UMLS Concept Unique Identifier: C0348439. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
How does D46.4 relate to ICF functioning codes?
ICF (International Classification of Functioning, Disability and Health) codes describe how conditions like refractory anemia, unspecified affect a person's functioning — body functions, activities, participation, and environmental factors. AutoICD provides ICF Core Sets for 12+ conditions and can map clinical text to ICF categories automatically. Browse the ICF directory to explore functioning codes.
What is the ICD-11 equivalent of D46.4?
D46.4 maps to the ICD-11 code: 2A30 (Refractory anaemia).
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.