E88.0
Non-billableDisorders of plasma-protein metabolism, NEC
Disorders of plasma-protein metabolism, not elsewhere classified
This is a header/category code. For billing purposes, use a more specific child code from the list below.
Coding Notes
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
- androgen insensitivity syndrome (E34.5-)
- congenital adrenal hyperplasia (E25.0)
- hemolytic anemias attributable to enzyme disorders (D55.-)
- Marfan syndrome (Q87.4-)
- 5-alpha-reductase deficiency (E29.1)
- histiocytosis X (chronic) (C96.6)
- monoclonal gammopathy (of undetermined significance) (D47.2)
- polyclonal hypergammaglobulinemia (D89.0)
- Waldenström macroglobulinemia (C88.00)
Excludes 2
Conditions not included here, but the patient may have both
Use Additional Code
Additional codes that should follow this code
- codes for associated conditions
Child Codes (3)
Also Known As / Clinical Terms
Frequently Asked Questions
What is ICD-10 code E88.0?
ICD-10-CM code E88.0 represents "Disorders of plasma-protein metabolism, not elsewhere classified". It is a non-billable header code — use a more specific child code for billing purposes.
Is E88.0 a billable code?
No, E88.0 is a non-billable header code. You need to use one of its more specific child codes for billing. There are 3 child codes under E88.0.
What chapter is E88.0 in?
E88.0 is in Chapter 4: Endocrine, Nutritional and Metabolic Diseases (codes E00-E89).
What codes cannot be used with E88.0?
E88.0 has Excludes1 notes indicating codes that cannot be used together with it, including: transitory endocrine and metabolic disorders specific to newborn (P70-P74); androgen insensitivity syndrome (E34.5-); congenital adrenal hyperplasia (E25.0); and 7 more.
What are the subcategories under E88.0?
E88.0 has 3 child codes, including: E88.01 (Alpha-1-antitrypsin deficiency), E88.02 (Plasminogen deficiency), E88.09 (Oth disorders of plasma-protein metabolism, NEC).
Are additional codes required with E88.0?
Yes, when using E88.0 you should also code: codes for associated conditions.
What are the UMLS CUIs for E88.0?
E88.0 is linked to 1 UMLS Concept Unique Identifier: C0494359. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.