D84.1
BillableDefects in the complement system
Defects in the complement system
Coding Notes
Inclusion Terms
Alternative clinical terms for this condition
- C1 esterase inhibitor [C1-INH] deficiency
Includes
Conditions included under this code
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes 1
Codes that cannot be used together with this code (mutual exclusion)
Excludes 2
Conditions not included here, but the patient may have both
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Also Known As / Clinical Terms
SNOMED CT
- Edema of mouth9067002
- Edema of oral soft tissues9067002
- Oedema of mouth9067002
- Oedema of oral soft tissues9067002
- Coombs negative haemolytic anaemia12189000
- Coombs negative hemolytic anemia12189000
- Complement abnormality18827005
- Acquired cutis laxa19726003
- Cutis laxa, acquired type19726003
- Disorder of complement24419001
- Complement deficiency disease24743004
- Defects in the complement system24743004
- Anaemia due to mechanical damage34247008
- Anemia due to mechanical damage34247008
- Familial C3B inhibitor deficiency syndrome39674000
- PLE - Protein-losing enteropathy66972006
- Protein-losing enteropathy66972006
- Gingival edema70346000
- Gingival oedema70346000
- Properdin deficiency81166004
- Properdin deficiency disease81166004
- HAE - Hereditary angio-oedema82966003
- HAE - Hereditary angioedema82966003
- HANE - Hereditary angioneurotic edema82966003
- HANE - Hereditary angioneurotic oedema82966003
- Hereditary Quincke's edema82966003
- Hereditary Quincke's oedema82966003
- Hereditary angio-oedema82966003
- Hereditary angioedema82966003
- Hereditary angioneurotic edema82966003
- Hereditary angioneurotic oedema82966003
- Classical complement pathway abnormality234593008
- Complement 1q deficiency234594002
- Complement 1q beta chain deficiency234595001
- Complement 1q dysfunction234596000
- Complement 1r deficiency234597009
- Complement 1s deficiency234598004
- Complement 2 deficiency234599007
- Complement 4 deficiency234600005
- C4AQ0 - Complement 4A deficiency234601009
- Complement 4A deficiency234601009
- C4BQ0 - Complement 4B deficiency234602002
- Complement 4B deficiency234602002
- Alternative pathway deficiency234604001
- Factor B deficiency234605000
- Factor D deficiency234607008
- Terminal component deficiency234608003
- Complement 5 deficiency234609006
- Complement 6 deficiency234611002
- Complement 7 deficiency234612009
- Combined complement 6 and 7 deficiencies234613004
- Complement 8 beta chain deficiency234614005
- Complement 8 beta chain dysfunction234615006
- Complement 8 alpha-gamma deficiency234616007
- Complement 9 deficiency234617003
- Complement regulatory factor defect234618008
- C1 esterase inhibitor deficiency - type 1234619000
- Hereditary C1 esterase inhibitor deficiency - deficient factor234619000
- Hereditary angio-oedema - type 1234619000
- Hereditary angioedema - type 1234619000
- Hereditary angioneurotic edema - type 1234619000
- Hereditary angioneurotic oedema - type 1234619000
- C1 esterase inhibitor deficiency - type 2234620006
- Hereditary C1 esterase inactivity234620006
- Hereditary C1 esterase inhibitor deficiency - dysfunctional factor234620006
- Hereditary angio-oedema - type 2234620006
- Hereditary angioedema - type 2234620006
- Hereditary angioneurotic edema - type 2234620006
- Hereditary angioneurotic oedema - type 2234620006
- Factor H deficiency234622003
- Complement 4 binding protein deficiency234623008
- CD55 - Cluster of differentiation antigen 55 deficiency234624002
- Decay accelerating factor deficiency234624002
- C8 binding protein deficiency234625001
- CD59 - Cluster of differentiation 59 deficiency234625001
- Homologous restriction factor deficiency234625001
- Complement 5a inhibitor deficiency234626000
- Anaphylotoxin inactivator deficiency234627009
- Carboxypeptidase N deficiency234627009
- Kininase I deficiency234627009
- Complement receptor deficiency234628004
- Complement receptor 1 deficiency234629007
- CR3 (complement receptor 3) deficiency234630002
- Complement receptor 3 deficiency234630002
- Acquired C1 esterase inhibitor deficiency241955009
- Acquired angio-oedema241955009
- Acquired angioedema241955009
- Acquired angioedema with C1Inh (C1 esterase inhibitor) deficiency241955009
- Acquired angioneurotic edema with C1 inhibitor deficiency241955009
- Acquired angioneurotic edema with C1Inh (C1 esterase inhibitor) deficiency241955009
- Acquired angioneurotic oedema with C1 inhibitor deficiency241955009
- Acquired angioneurotic oedema with C1Inh (C1 esterase inhibitor) deficiency241955009
- Complement 5 dysfunction263661007
- Complement component deficiency363009005
- Autoimmune angio-oedema402401003
- Autoimmune angioedema402401003
- Autoimmune urticaria and/or angio-oedema402402005
- Autoimmune urticaria and/or angioedema402402005
- Panniculitis due to immunological disorder402686000
- Cutis laxa with complement deficiency403400008
- Panniculitis with complement deficiency403414008
- Recurrent bacterial infection428875002
- Angio-oedema due to disorder of kinin metabolism703795004
- Angioedema due to disorder of kinin metabolism703795004
- Acquired angio-oedema due to C1 inhibitor autoantibody703802001
- Acquired angioedema due to C1 inhibitor autoantibody703802001
- Immunodeficiency due to MASP-2 (mannan binding lectin serine peptidase 2) deficiency771078002
- Immunodeficiency due to MASP-2 deficiency771078002
- Immunodeficiency due to mannan binding lectin serine peptidase 2 deficiency771078002
- C3 deficiency771443008
- Complement component 3 deficiency771443008
- Primary CD59 deficiency778027003
- Recurrent Neisseria infection due to factor D deficiency783007005
- Atypical haemolytic uraemic syndrome789660001
- Atypical hemolytic uremic syndrome789660001
- aHUS - atypical haemolytic uraemic syndrome789660001
- aHUS - atypical hemolytic uremic syndrome789660001
- Disorder of glomerulus due to complement system disorder1148884002
- Glomerular disease due to complement system disorder1148884002
- C8 (complement component 8) deficiency1162263002
- Complement component 8 deficiency1162263002
- Angioedema of gingiva due to deficiency of C1 esterase inhibitor1197183009
- HAE (hereditary angioedema) with C1Inh (C1 esterase inhibitor) deficiency1230015008
- Hereditary angioedema with C1 esterase inhibitor deficiency1230015008
- Hereditary angioedema with C1Inh (C1 esterase inhibitor) deficiency1230015008
- Hereditary angioneurotic edema with C1 inhibitor deficiency1230015008
- Hereditary angioneurotic oedema with C1 inhibitor deficiency1230015008
- CHAPLE (complement hyperactivation, angiopathic thrombosis, protein losing enteropathy) syndrome1279887007
- CHAPLE syndrome1279887007
- Complement hyperactivation, angiopathic thrombosis, protein losing enteropathy syndrome1279887007
- Atypical haemolytic uraemic syndrome with complement gene abnormality1293264009
- Atypical hemolytic uremic syndrome with complement gene abnormality1293264009
- aHUS (atypical haemolytic uraemic syndrome) with complement gene abnormality1293264009
- aHUS (atypical hemolytic uremic syndrome) with complement gene abnormality1293264009
- Atypical HUS (haemolytic uraemic syndrome) with anti-CFH (complement factor H) Ab1295220004
- Atypical HUS (hemolytic uremic syndrome) with anti-CFH (complement factor H) Ab1295220004
- Atypical haemolytic uraemic syndrome with anti-factor H antibodies1295220004
- Atypical hemolytic uremic syndrome with anti-factor H antibodies1295220004
- aHUS (atypical haemolytic uraemic syndrome) with anti-factor H antibodies1295220004
- aHUS (atypical hemolytic uremic syndrome) with anti-factor H antibodies1295220004
UMLS
- C1 esterase inhibitor [C1-INH] deficiencyC2873848
- Complement DeficienciesC0272242
- Complement DeficiencyC0272242
- Complement deficiency diseaseC0272242
- Complement deficiency disease (disorder)C0272242
- Defects in the complement systemC0272242
- complement deficienciesC0272242
- complement deficiencyC0272242
- defects in the complement systemC0272242
- deficiency complementC0272242
Frequently Asked Questions
What is ICD-10 code D84.1?
ICD-10-CM code D84.1 represents "Defects in the complement system". It is a billable/specific code that can be used on a claim.
Is D84.1 a billable code?
Yes, D84.1 is a billable/specific ICD-10-CM code and can be used to indicate a diagnosis on a medical claim.
What chapter is D84.1 in?
D84.1 is in Chapter 3: Diseases of the Blood and Blood-Forming Organs (codes D50-D89).
What codes cannot be used with D84.1?
D84.1 has Excludes1 notes indicating codes that cannot be used together with it, including: autoimmune disease (systemic) NOS (M35.9); functional disorders of polymorphonuclear neutrophils (D71); human immunodeficiency virus [HIV] disease (B20).
What SNOMED CT codes does D84.1 map to?
D84.1 maps to 69 SNOMED CT concepts: 241955009, 703802001, 19726003, 234604001, 34247008, and 64 more. SNOMED CT is a clinical terminology used in electronic health records.
What are the UMLS CUIs for D84.1?
D84.1 is linked to 2 UMLS Concept Unique Identifiers: C2873848, C0272242. The UMLS (Unified Medical Language System) integrates multiple biomedical vocabularies maintained by the U.S. National Library of Medicine.
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Includes SNOMED Clinical Terms® (SNOMED CT®) used by permission of SNOMED International. Includes content from the UMLS Metathesaurus, courtesy of the U.S. National Library of Medicine.