97913-8
LaboratoryThrombin peak [Molar amount] in Platelet poor plasma by Chromogenic method --after addition of factor VIII Ab
Definition
The peak thrombin is the maximum thrombin measurement during a thrombin generation test. Decreased peak thrombin is associated with bleeding tendencies, while increased peak thrombin is associated with thrombosis. [PMID: 21262433] If the peak is significantly decreased in the presence of Factor VIII antibodies, that indicates that Factor VIII had a significant contribution to the baseline thrombin peak (measured without Factor VIII antibodies). [PMID: 12871369]
LOINC 6-Axis Classification
Component
Thrombin peak^after addition of Factor VIII Ab
Property
Sub
Time Aspect
Pt
System
PPP
Scale Type
Qn
Method Type
Chromo
Details
Class
COAG
Order/Observation
Observation
Short Name
Thrombin peak p FVIII Ab sub PPP Qn Chro
Display Name
Thrombin peak after addition of factor VIII Ab Chromogenic method (PPP) [Molar amount]
Related Names
Frequently Asked Questions
What is LOINC code 97913-8?
LOINC code 97913-8 identifies "Thrombin peak [Molar amount] in Platelet poor plasma by Chromogenic method --after addition of factor VIII Ab". The peak thrombin is the maximum thrombin measurement during a thrombin generation test. Decreased peak thrombin is associated with bleeding tendencies, while increased peak thrombin is associated with thrombosis. [PMID: 21262433] If the peak is significantly decreased in the presence of Factor VIII antibodies, that indicates that Factor VIII had a significant contribution to the baseline thrombin peak (measured without Factor VIII antibodies). [PMID: 12871369]
What does 97913-8 measure?
This code measures Thrombin peak^after addition of Factor VIII Ab in PPP. It belongs to the COAG class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.