97911-2
LaboratoryEndogenous thrombin potential [Area under the curve] in Platelet poor plasma by Chromogenic method --after addition of factor VIII Ab
Definition
The endogenous thrombin potential (ETP) is the area under the curve of a thrombin generation test (TGT). It represents thrombin's total enzyme activity and is the most predictive of bleeding and/or thrombosis risk out of all the TGT measurements. [PMID: 21262433] Measuring the ETP in the presence of Factor VIII antibodies is done to help determine the contribution of Factor VIII to the ETP. If the ETP is significantly decreased in the presence of Factor VIII antibodies, that indicates that Factor VIII had a significant contribution to the baseline ETP. If the ETP does not decrease, then Factor VIII did not have a large contribution. [PMID: 12871369]
LOINC 6-Axis Classification
Component
Endogenous thrombin potential^after addition of Factor VIII Ab
Property
TmSCnc
Time Aspect
Pt
System
PPP
Scale Type
Qn
Method Type
Chromo
Details
Class
COAG
Order/Observation
Both
Short Name
ETP p FVIII Ab PPP Chro-AUC
Display Name
Endogenous thrombin potential after addition of factor VIII Ab Chromogenic method (PPP) [Area under the curve]
Related Names
Frequently Asked Questions
What is LOINC code 97911-2?
LOINC code 97911-2 identifies "Endogenous thrombin potential [Area under the curve] in Platelet poor plasma by Chromogenic method --after addition of factor VIII Ab". The endogenous thrombin potential (ETP) is the area under the curve of a thrombin generation test (TGT). It represents thrombin's total enzyme activity and is the most predictive of bleeding and/or thrombosis risk out of all the TGT measurements. [PMID: 21262433] Measuring the ETP in the presence of Factor VIII antibodies is done to help determine the contribution of Factor VIII to the ETP. If the ETP is significantly decreased in the presence of Factor VIII antibodies, that indicates that Factor VIII had a significant contribution to the baseline ETP. If the ETP does not decrease, then Factor VIII did not have a large contribution. [PMID: 12871369]
What does 97911-2 measure?
This code measures Endogenous thrombin potential^after addition of Factor VIII Ab in PPP. It belongs to the COAG class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.