AutoICD API

97760-3

Laboratory

MLH1 gene methylation analysis in Blood by Molecular genetics method

Definition

MLH1 gene methylation analysis in blood is performed as an adjunct to positive hypermethylation in tumor to distinguish between somatic and germline hypermethylation, or as an adjunct to negative MLH1 germline testing in cases where colon or endometrial tumor demonstrates microsatellite instability-H (MSI-H) and loss of MLH1 protein expression.

LOINC 6-Axis Classification

Component

MLH1 gene methylation analysis

Property

Find

Time Aspect

Pt

System

Bld

Scale Type

Doc

Method Type

Molgen

Details

Class

MOLPATH

Order/Observation

Both

Short Name

MLH1 Methyl Anl Bld

Display Name

MLH1 gene methylation analysis Molgen Doc (Bld)

Related Names

BloodCOCA2DNA methylationDocumentFCC2FindingFindingshMLH1HNPCCHNPCC2Lynch syndromeMGC5172MLH1 Methyl AnlMolecular geneticsMolecular pathologyMOLPATHmutL homolog 1MutL homolog 1, colon cancer, nonpolyposis type 2PCRPoint in timeRandomWBWhole blood

Frequently Asked Questions

What is LOINC code 97760-3?

LOINC code 97760-3 identifies "MLH1 gene methylation analysis in Blood by Molecular genetics method". MLH1 gene methylation analysis in blood is performed as an adjunct to positive hypermethylation in tumor to distinguish between somatic and germline hypermethylation, or as an adjunct to negative MLH1 germline testing in cases where colon or endometrial tumor demonstrates microsatellite instability-H (MSI-H) and loss of MLH1 protein expression.

What does 97760-3 measure?

This code measures MLH1 gene methylation analysis in Bld. It belongs to the MOLPATH class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.