96981-6
LaboratoryTrisomy 13, trisomy 18 or triploidy risk [Likelihood] in Plasma cell-free+WBC DNA by calculation
Definition
The combined fetal trisomy 13+trisomy 18+triploidy risk value is calculated in cases where the SNP-based noninvasive prenatal test did not return a result due to low fetal fraction (FF) or the inability to make a high-confidence call. FF is known to be lower in cases of trisomy 13, trisomy 18 and digynic (maternal) triploidy, but not all cases of low FF is due to aneuploidy. Combined risk calculations may include the FF value, gestational age (GA), maternal weight (MW) and prior risk data to determine the overall risk. [PMID: 30014528]
LOINC 6-Axis Classification
Component
Fetal trisomy 13+trisomy 18+triploidy risk
Property
Likelihood
Time Aspect
Pt
System
WBC.DNA+Plas.cfDNA
Scale Type
Qn
Method Type
Calculated
Details
Class
MOLPATH
Order/Observation
Observation
Short Name
T13+T18+Trip risk WBC.DNA+cfDNA Calc
Display Name
Trisomy 13, trisomy 18 or triploidy risk Calc Qn (Plasma cell-free+WBC DNA)
Related Names
Frequently Asked Questions
What is LOINC code 96981-6?
LOINC code 96981-6 identifies "Trisomy 13, trisomy 18 or triploidy risk [Likelihood] in Plasma cell-free+WBC DNA by calculation". The combined fetal trisomy 13+trisomy 18+triploidy risk value is calculated in cases where the SNP-based noninvasive prenatal test did not return a result due to low fetal fraction (FF) or the inability to make a high-confidence call. FF is known to be lower in cases of trisomy 13, trisomy 18 and digynic (maternal) triploidy, but not all cases of low FF is due to aneuploidy. Combined risk calculations may include the FF value, gestational age (GA), maternal weight (MW) and prior risk data to determine the overall risk. [PMID: 30014528]
What does 96981-6 measure?
This code measures Fetal trisomy 13+trisomy 18+triploidy risk in WBC.DNA+Plas.cfDNA. It belongs to the MOLPATH class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.