96979-0
LaboratoryTrisomy 13, trisomy 18 or triploidy risk [Interpretation] in Plasma cell-free+WBC DNA Qualitative by calculation
Definition
The ordinal interpretation for the combined fetal trisomy 13+trisomy 18+triploidy risk is determined in cases where the SNP-based noninvasive prenatal test did not return a result due to low fetal fraction (FF) or the inability to make a high-confidence call. FF is known to be lower in cases of trisomy 13, trisomy 18 and digynic (maternal) triploidy, but not all cases of low FF is due to aneuploidy. Combined risk calculations may include the FF value, gestational age (GA), maternal weight (MW) and prior risk data to determine the overall risk.[PMID: 30014528]
LOINC 6-Axis Classification
Component
Fetal trisomy 13+trisomy 18+triploidy risk
Property
Imp
Time Aspect
Pt
System
WBC.DNA+Plas.cfDNA
Scale Type
Ord
Method Type
Calculated
Details
Class
MOLPATH
Order/Observation
Observation
Short Name
T13+T18+Trip risk WBC.DNA+cfDNA Calc-Imp
Display Name
Trisomy 13, trisomy 18 or triploidy risk Calc Ql (Plasma cell-free+WBC DNA) [Interp]
Related Names
Frequently Asked Questions
What is LOINC code 96979-0?
LOINC code 96979-0 identifies "Trisomy 13, trisomy 18 or triploidy risk [Interpretation] in Plasma cell-free+WBC DNA Qualitative by calculation". The ordinal interpretation for the combined fetal trisomy 13+trisomy 18+triploidy risk is determined in cases where the SNP-based noninvasive prenatal test did not return a result due to low fetal fraction (FF) or the inability to make a high-confidence call. FF is known to be lower in cases of trisomy 13, trisomy 18 and digynic (maternal) triploidy, but not all cases of low FF is due to aneuploidy. Combined risk calculations may include the FF value, gestational age (GA), maternal weight (MW) and prior risk data to determine the overall risk.[PMID: 30014528]
What does 96979-0 measure?
This code measures Fetal trisomy 13+trisomy 18+triploidy risk in WBC.DNA+Plas.cfDNA. It belongs to the MOLPATH class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.