96649-9
LaboratoryHLA-DPB1 T-cell epitope match [Type] in Donor+Patient by High resolution
Definition
Matching of HLA alleles between unrelated donors and transplant recipients is undertaken to reduce the risk of graft versus host disease to the greatest extent possible. However, it has been shown that HLA-DPB1 matched unrelated donors are often difficult to find. As a result HLA-DPB1 alleles have been placed into groups, so that HLA-DPB1 mismatches between donor and recipient can be classified as "permissive mismatches" (which have a greater chance of success) versus "non-permissive" [PMID:22340965].
LOINC 6-Axis Classification
Component
HLA-DPB1 T-cell epitope match
Property
Type
Time Aspect
Pt
System
Bld/Tiss^Donor+Patient
Scale Type
Nom
Method Type
High resolution
Details
Class
HLA
Order/Observation
Observation
Short Name
HLA-DPB1 Ept Match Don+Pt High Res
Display Name
HLA-DPB1 T-cell epitope match High resolution Nom (Bld/Tiss Donor+Patient)
Related Names
Frequently Asked Questions
What is LOINC code 96649-9?
LOINC code 96649-9 identifies "HLA-DPB1 T-cell epitope match [Type] in Donor+Patient by High resolution". Matching of HLA alleles between unrelated donors and transplant recipients is undertaken to reduce the risk of graft versus host disease to the greatest extent possible. However, it has been shown that HLA-DPB1 matched unrelated donors are often difficult to find. As a result HLA-DPB1 alleles have been placed into groups, so that HLA-DPB1 mismatches between donor and recipient can be classified as "permissive mismatches" (which have a greater chance of success) versus "non-permissive" [PMID:22340965].
What does 96649-9 measure?
This code measures HLA-DPB1 T-cell epitope match in Bld/Tiss^Donor+Patient. It belongs to the HLA class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.