94753-1

LOINC code 94753-1 identifies "Psychotropic medication pharmacogenomic analysis in Blood or Tissue by Molecular genetics method". A comprehensive analysis for multiple genes that have strong pharmacogenomic associations with medications used in the treatment of psychiatric disorders, including depression. Each sample is tested for specific genetic variations with known functional impact. Depending on the lab, this test may include targeted analysis for following genes: ANKK1, ADRA2, CHRNA3, COMT, CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5, DRD2, EPHX1, GRIK4, HLA-A (such as HLA-A*31:01 allele), HLA-B (such as HLA-B*15:02 allele), HTR2A, HTR2C, MTHFR, OPRM1, SCN1A, SLC6A4 (5-HTT), and UGT2B15. Duplications and multiplications of alleles may also be identified. Various genotyping assay methods, such as real-time PCR, sequencing, and deletion/duplication analysis, may be used.

This code measures Psychotropic medication pharmacogenomic analysis in Bld/Tiss. It belongs to the MOLPATH.PHARMG class in the LOINC classification.

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.