94718-4
LaboratoryAlpha defensins 1+2+3 [Presence] in Synovial fluid by Immunoassay
Definition
Qualitative detection of human neutrophil peptide-1, -2, and -3, also known as alpha defensins 1-3, in synovial fluid by immunoassay methods, such as ELISA or lateral flow assay, for the diagnosis of periprosthetic joint infections (PJI). This assay detects but does not differentiate between the three HNP peptides. This term was created for, but not limited in use to, Zimmer Biomet Diagnostics Synovasure Alpha Defensin ELISA and Lateral Flow Test kits. The Synovasure Lateral flow test utilizes the same anti-microbial peptide as the ELISA test to detect the immune response to infection, but the Lateral Flow returns results in 10 minute whereas the ELISA typically has a 24-48 hour result turnaround.
LOINC 6-Axis Classification
Component
Alpha defensins 1+2+3
Property
PrThr
Time Aspect
Pt
System
Synv fld
Scale Type
Ord
Method Type
IA
Details
Class
CHEM
Order/Observation
Both
Short Name
Alpha defensins 1+2+3 Snv Ql IA
Display Name
Alpha defensins 1+2+3 IA Ql (Syn fld)
Related Names
Frequently Asked Questions
What is LOINC code 94718-4?
LOINC code 94718-4 identifies "Alpha defensins 1+2+3 [Presence] in Synovial fluid by Immunoassay". Qualitative detection of human neutrophil peptide-1, -2, and -3, also known as alpha defensins 1-3, in synovial fluid by immunoassay methods, such as ELISA or lateral flow assay, for the diagnosis of periprosthetic joint infections (PJI). This assay detects but does not differentiate between the three HNP peptides. This term was created for, but not limited in use to, Zimmer Biomet Diagnostics Synovasure Alpha Defensin ELISA and Lateral Flow Test kits. The Synovasure Lateral flow test utilizes the same anti-microbial peptide as the ELISA test to detect the immune response to infection, but the Lateral Flow returns results in 10 minute whereas the ELISA typically has a 24-48 hour result turnaround.
What does 94718-4 measure?
This code measures Alpha defensins 1+2+3 in Synv fld. It belongs to the CHEM class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.