94449-6
LaboratoryHLA-A and B and C (class I) IgG high risk [Identifier] in Serum or Plasma by Flow cytometry (FC)
Definition
Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in the higher risk stratification of MFI values (For one lab this was MFI > 5000, but some laboratories use 10,000 or another value).
LOINC 6-Axis Classification
Component
HLA-A & B & C (class I) Ab.IgG high risk
Property
Prid
Time Aspect
Pt
System
Ser/Plas
Scale Type
Nom
Method Type
Flow cytometry
Details
Class
HLA
Order/Observation
Observation
Short Name
HLA class I Ab.IgG high risk SerPl FC
Display Name
HLA-A & B & C (class I) Ab.IgG high risk FC Nom
Related Names
Frequently Asked Questions
What is LOINC code 94449-6?
LOINC code 94449-6 identifies "HLA-A and B and C (class I) IgG high risk [Identifier] in Serum or Plasma by Flow cytometry (FC)". Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in the higher risk stratification of MFI values (For one lab this was MFI > 5000, but some laboratories use 10,000 or another value).
What does 94449-6 measure?
This code measures HLA-A & B & C (class I) Ab.IgG high risk in Ser/Plas. It belongs to the HLA class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.