94448-8
LaboratoryHLA-DP and DQ and DR (class II) IgG intermediate risk [Identifier] in Serum or Plasma by Flow cytometry (FC)
Definition
Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in an intermediate risk stratification of MFI values (For one lab this was 4999 > MFI > 2000, but some laboratories use other values).
LOINC 6-Axis Classification
Component
HLA-DP & DQ & DR (class II) Ab.IgG intermediate risk
Property
Prid
Time Aspect
Pt
System
Ser/Plas
Scale Type
Nom
Method Type
Flow cytometry
Details
Class
HLA
Order/Observation
Observation
Short Name
HLA class II Ab.IgG med risk SerPl FC
Display Name
HLA-DP & DQ & DR (class II) Ab.IgG intermediate risk FC Nom
Related Names
Frequently Asked Questions
What is LOINC code 94448-8?
LOINC code 94448-8 identifies "HLA-DP and DQ and DR (class II) IgG intermediate risk [Identifier] in Serum or Plasma by Flow cytometry (FC)". Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in an intermediate risk stratification of MFI values (For one lab this was 4999 > MFI > 2000, but some laboratories use other values).
What does 94448-8 measure?
This code measures HLA-DP & DQ & DR (class II) Ab.IgG intermediate risk in Ser/Plas. It belongs to the HLA class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.