94442-1
LaboratoryHLA-A and B and C (class I) IgG with prozone effect [Identifier] in Serum or Plasma by Flow cytometry (FC)
Definition
Sometimes high titer antibody can be associated with low levels of detection (low mean fluorescence intensity, MFI, for the Luminex HLA bead assay), a phenomenon often referred to as the "prozone" effect. This term is intended to report those antibodies that were not detected with original sample, but became detectable after dilution or assay treatment. Some laboratories refer to these "prozone antigens observed", meaning those antigens for which the patient's antibody exhibited prozone effect.
LOINC 6-Axis Classification
Component
HLA-A & B & C (class I) Ab.IgG with prozone effect
Property
Prid
Time Aspect
Pt
System
Ser/Plas
Scale Type
Nom
Method Type
Flow cytometry
Details
Class
HLA
Order/Observation
Observation
Short Name
HLA class I Ab.IgG prozone SerPl FC
Display Name
HLA-A & B & C (class I) Ab.IgG with prozone effect FC Nom
Related Names
Frequently Asked Questions
What is LOINC code 94442-1?
LOINC code 94442-1 identifies "HLA-A and B and C (class I) IgG with prozone effect [Identifier] in Serum or Plasma by Flow cytometry (FC)". Sometimes high titer antibody can be associated with low levels of detection (low mean fluorescence intensity, MFI, for the Luminex HLA bead assay), a phenomenon often referred to as the "prozone" effect. This term is intended to report those antibodies that were not detected with original sample, but became detectable after dilution or assay treatment. Some laboratories refer to these "prozone antigens observed", meaning those antigens for which the patient's antibody exhibited prozone effect.
What does 94442-1 measure?
This code measures HLA-A & B & C (class I) Ab.IgG with prozone effect in Ser/Plas. It belongs to the HLA class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.