AutoICD API

94430-6

Laboratory

HLA-A and B and C (class I) IgG low risk [Identifier] in Serum or Plasma by Flow cytometry (FC)

Definition

Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in the lower risk stratification of MFI values, but still detectable and possibly having a risk of rejection (For one lab this range was 500 < MFI < 1999).

LOINC 6-Axis Classification

Component

HLA-A & B & C (class I) Ab.IgG low risk

Property

Prid

Time Aspect

Pt

System

Ser/Plas

Scale Type

Nom

Method Type

Flow cytometry

Details

Class

HLA

Order/Observation

Observation

Short Name

HLA class I Ab.IgG low risk SerPl FC

Display Name

HLA-A & B & C (class I) Ab.IgG low risk FC Nom

Related Names

A,BDynamicFCGeneticsHeredityHeritableHLA ANTIGENHLA class IHLA class I Ab.IgG low riskHLA-A+BHLA-A+B+CHLA-A+B+C (class I)Human Leukocyte AntigenIdentity or presenceImmune globulin GImmunoglobulin GInheritedNominalPlPlasmaPlsmPoint in timeRandomSerPSerPlSerPlasSerumSerum or plasmaSR

Frequently Asked Questions

What is LOINC code 94430-6?

LOINC code 94430-6 identifies "HLA-A and B and C (class I) IgG low risk [Identifier] in Serum or Plasma by Flow cytometry (FC)". Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in the lower risk stratification of MFI values, but still detectable and possibly having a risk of rejection (For one lab this range was 500 < MFI < 1999).

What does 94430-6 measure?

This code measures HLA-A & B & C (class I) Ab.IgG low risk in Ser/Plas. It belongs to the HLA class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.