AutoICD API

94403-3

Laboratory

CHRNA3 gene c.645C>T [Genotype] in Blood or Tissue by Molecular genetics method Nominal

Definition

The patient's genotype for the c.645C>T (D398N, rs1051730) variant in the CHRNA3 (nicotinic acetylcholine receptor alpha 3 subunit) gene. The rs1051730(T) allele is associated with nicotine dependence, cigarette consumption, smoking cessation, lung cancer risk, and COPD.[PMID: 26751916]

LOINC 6-Axis Classification

Component

CHRNA3 gene.c.645C>T

Property

Geno

Time Aspect

Pt

System

Bld/Tiss

Scale Type

Nom

Method Type

Molgen

Details

Class

MOLPATH.PHARMG

Order/Observation

Observation

Short Name

CHRNA3 c.645C>T Geno Bld/T

Display Name

CHRNA3 gene c.645C>T genotype Molgen (Bld/Tiss)

Related Names

BloodCHRNA3 c.645C&gtTD398NGeneticsHeredityHeritableInheritedMolecular geneticsMolecular pathologyMOLPATHMOLPATH.PHARMGNominalPCRPoint in timeRandomrs1051730T primeTissueTissue, unspecifiedWBWhole bloodWhole blood or Tissue

Frequently Asked Questions

What is LOINC code 94403-3?

LOINC code 94403-3 identifies "CHRNA3 gene c.645C>T [Genotype] in Blood or Tissue by Molecular genetics method Nominal". The patient's genotype for the c.645C>T (D398N, rs1051730) variant in the CHRNA3 (nicotinic acetylcholine receptor alpha 3 subunit) gene. The rs1051730(T) allele is associated with nicotine dependence, cigarette consumption, smoking cessation, lung cancer risk, and COPD.[PMID: 26751916]

What does 94403-3 measure?

This code measures CHRNA3 gene.c.645C>T in Bld/Tiss. It belongs to the MOLPATH.PHARMG class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.