94266-4
LaboratoryCD11a, CD11b, and CD18 phenotyping panel - Blood Qualitative
Definition
Flow cytometric immunophenotyping evaluation for presence or absence of the CD11/CD18 complex using monoclonal antibodies directed against the CD11 isoforms, CD11a and CD11b, and CD18 antigens. Defects in CD18 expression lead to either very low or no surface membrane expression of alpha chains CD11a, CD11b, and CD11c. Testing is performed for the diagnosis of leukocyte adhesion deficiency syndrome type 1 (LAD-1), an autosomal recessive disorder caused by mutations in the common chain (CD18) of the beta2-integrin family.
LOINC 6-Axis Classification
Component
CD11a & CD11b & CD18 phenotyping panel
Property
-
Time Aspect
Pt
System
Bld
Scale Type
Ord
Method Type
N/A
Details
Class
PANEL.CELLMARK
Order/Observation
Order
Short Name
CD11a + CD11b + CD18 Pnl Bld
Display Name
CD11a, CD11b, and CD18 phenotyping panel Ql (Bld)
Related Names
Frequently Asked Questions
What is LOINC code 94266-4?
LOINC code 94266-4 identifies "CD11a, CD11b, and CD18 phenotyping panel - Blood Qualitative". Flow cytometric immunophenotyping evaluation for presence or absence of the CD11/CD18 complex using monoclonal antibodies directed against the CD11 isoforms, CD11a and CD11b, and CD18 antigens. Defects in CD18 expression lead to either very low or no surface membrane expression of alpha chains CD11a, CD11b, and CD11c. Testing is performed for the diagnosis of leukocyte adhesion deficiency syndrome type 1 (LAD-1), an autosomal recessive disorder caused by mutations in the common chain (CD18) of the beta2-integrin family.
What does 94266-4 measure?
This code measures CD11a & CD11b & CD18 phenotyping panel in Bld. It belongs to the PANEL.CELLMARK class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.