AutoICD API

94221-9

Laboratory

SMN1 gene full mutation analysis in Blood or Tissue by Sequencing

Definition

Full gene sequencing of the SMN1 gene, including all protein-coding regions and intron/exon boundaries of the gene. Testing is performed to confirm a diagnosis of spinal muscular atrophy (SMA) due to variants in SMN1 gene. This test is also used for at-risk family members who have a family history of spinal muscular atrophy but an affected individual is not available for testing, or when disease-causing mutations are unknown.

LOINC 6-Axis Classification

Component

SMN1 gene full mutation analysis

Property

Find

Time Aspect

Pt

System

Bld/Tiss

Scale Type

Doc

Method Type

Sequencing

Details

Class

MOLPATH

Order/Observation

Both

Short Name

SMN1 gene Full Mut Anl Bld/T Seq

Display Name

SMN1 gene full mutation analysis Sequencing Doc (Bld/Tiss)

Related Names

BCD541BloodDocumentFindingFindingsfull gene sequencingFull Mut AnlGemin 1GEMIN1GeneticsHeredityHeritablehigh-throughput sequencingHTSInheritedKugelberg-Welander diseaseMolecular pathologyMOLPATHMutMutationsNext generation sequencingNGSPoint in timeRandomsequencing of entire coding regionSMASMA geneSMA@SMA1SMA2SMA3SMA4SMNSMNTSMVspinal muscular atrophySurvival motor neuron protein genesurvival of motor neuron 1, telomericT-BCD541TDRD16ATissueTissue, unspecifiedWBWerdnig-Hoffmann diseaseWhole bloodWhole blood or Tissue

Frequently Asked Questions

What is LOINC code 94221-9?

LOINC code 94221-9 identifies "SMN1 gene full mutation analysis in Blood or Tissue by Sequencing". Full gene sequencing of the SMN1 gene, including all protein-coding regions and intron/exon boundaries of the gene. Testing is performed to confirm a diagnosis of spinal muscular atrophy (SMA) due to variants in SMN1 gene. This test is also used for at-risk family members who have a family history of spinal muscular atrophy but an affected individual is not available for testing, or when disease-causing mutations are unknown.

What does 94221-9 measure?

This code measures SMN1 gene full mutation analysis in Bld/Tiss. It belongs to the MOLPATH class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.