AutoICD API

94186-4

Laboratory

Origin of germline genetic variant [Type]

Definition

The source or inheritance of a specific germline variation found in an individual patient. Understanding the source can help determine the significance of a particular variant and its association with different diseases or syndromes. Germline variants are either inherited or de novo. Inherited variants can be maternal, paternal, or a combination of maternal and paternal. De novo variants are those that are not present in parental germline cells, but that arise in the egg or sperm prior to conception or just after the zygote is formed. [PMID: 27894357]

LOINC 6-Axis Classification

Component

Origin of germline genetic variant

Property

Type

Time Aspect

Pt

System

^Patient

Scale Type

Nom

Method Type

N/A

Details

Class

MOLPATH

Order/Observation

Observation

Short Name

Origin germline gen var

Display Name

Origin of germline genetic variant Nom

Related Names

GeneticsGenomicHeredityHeritableInheritedMolecular pathologyMOLPATHNominalOrigin germline gen varPoint in timeRandomTyp

Frequently Asked Questions

What is LOINC code 94186-4?

LOINC code 94186-4 identifies "Origin of germline genetic variant [Type]". The source or inheritance of a specific germline variation found in an individual patient. Understanding the source can help determine the significance of a particular variant and its association with different diseases or syndromes. Germline variants are either inherited or de novo. Inherited variants can be maternal, paternal, or a combination of maternal and paternal. De novo variants are those that are not present in parental germline cells, but that arise in the egg or sperm prior to conception or just after the zygote is formed. [PMID: 27894357]

What does 94186-4 measure?

This code measures Origin of germline genetic variant in ^Patient. It belongs to the MOLPATH class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.