93852-2
LaboratoryN-Acetylgalactosamine-4-Sulfatase/N-Acetylgalactosamine-6-Sulfatase [Enzymatic activity ratio] in Urine
Definition
The ratio of N-acetylgalactosamine 4-sulfatase to N-acetylgalactosamine 6-sulfatase helps differentiate between Morquio A syndrome and Maroteaux-Lamy syndrome. Morquio A syndrome (mucopolysaccharidosis type IVA) is associated with a deficiency of N-acetylgalactosamine 6-sulfatase, while Maroteaux-Lamy syndrome (mucopolysaccharidosis VI), is associated with a loss or decreased activity of N-acetylgalactosamine 4-sulfatase.
LOINC 6-Axis Classification
Component
N-acetylgalactosamine-4-sulfatase/N-acetylgalactosamine-6-sulfatase
Property
CRto
Time Aspect
Pt
System
Urine
Scale Type
Qn
Method Type
N/A
Details
Class
CHEM
Order/Observation
Both
Short Name
Arylsulfatase B/GALNS Ur-cRto
Display Name
N-Acetylgalactosamine-4-Sulfatase/N-Acetylgalactosamine-6-Sulfatase (U) [Catalytic ratio]
Related Names
Frequently Asked Questions
What is LOINC code 93852-2?
LOINC code 93852-2 identifies "N-Acetylgalactosamine-4-Sulfatase/N-Acetylgalactosamine-6-Sulfatase [Enzymatic activity ratio] in Urine". The ratio of N-acetylgalactosamine 4-sulfatase to N-acetylgalactosamine 6-sulfatase helps differentiate between Morquio A syndrome and Maroteaux-Lamy syndrome. Morquio A syndrome (mucopolysaccharidosis type IVA) is associated with a deficiency of N-acetylgalactosamine 6-sulfatase, while Maroteaux-Lamy syndrome (mucopolysaccharidosis VI), is associated with a loss or decreased activity of N-acetylgalactosamine 4-sulfatase.
What does 93852-2 measure?
This code measures N-acetylgalactosamine-4-sulfatase/N-acetylgalactosamine-6-sulfatase in Urine. It belongs to the CHEM class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.