93813-4
LaboratoryNTRK1, NTRK2 and NTRK3 gene rearrangements in Tissue by Molecular genetics method
Definition
This test detects fusions (rearrangements) involving the NTRK1, NTRK2, and NTKR3 genes to identify solid tumors that may respond to NTRK-targeted therapies. These NTRK genes rearrange with more than 80 fusion gene partners, leading to tumorigenesis across a variety of tumor types.[PMID: 31075511] The collection of information contained by this term may include the test method(s), targeted fusion variants, the overall result (fusion variant detected/not detected), the fusion variant identified, the interpretation, recommendations, references and clinical trial information.
LOINC 6-Axis Classification
Component
NTRK1 gene & NTRK2 gene & NTRK3 gene rearrangements
Property
Find
Time Aspect
Pt
System
Tiss
Scale Type
Doc
Method Type
Molgen
Details
Class
MOLPATH.PHARMG
Order/Observation
Both
Short Name
NTRK1+NTRK2+NTRK3 rearr Tiss
Display Name
NTRK1, NTRK2 and NTRK3 gene rearrangements Molgen Doc (Tiss)
Related Names
Frequently Asked Questions
What is LOINC code 93813-4?
LOINC code 93813-4 identifies "NTRK1, NTRK2 and NTRK3 gene rearrangements in Tissue by Molecular genetics method". This test detects fusions (rearrangements) involving the NTRK1, NTRK2, and NTKR3 genes to identify solid tumors that may respond to NTRK-targeted therapies. These NTRK genes rearrange with more than 80 fusion gene partners, leading to tumorigenesis across a variety of tumor types.[PMID: 31075511] The collection of information contained by this term may include the test method(s), targeted fusion variants, the overall result (fusion variant detected/not detected), the fusion variant identified, the interpretation, recommendations, references and clinical trial information.
What does 93813-4 measure?
This code measures NTRK1 gene & NTRK2 gene & NTRK3 gene rearrangements in Tiss. It belongs to the MOLPATH.PHARMG class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.