AutoICD API

93813-4

Laboratory

NTRK1, NTRK2 and NTRK3 gene rearrangements in Tissue by Molecular genetics method

Definition

This test detects fusions (rearrangements) involving the NTRK1, NTRK2, and NTKR3 genes to identify solid tumors that may respond to NTRK-targeted therapies. These NTRK genes rearrange with more than 80 fusion gene partners, leading to tumorigenesis across a variety of tumor types.[PMID: 31075511] The collection of information contained by this term may include the test method(s), targeted fusion variants, the overall result (fusion variant detected/not detected), the fusion variant identified, the interpretation, recommendations, references and clinical trial information.

LOINC 6-Axis Classification

Component

NTRK1 gene & NTRK2 gene & NTRK3 gene rearrangements

Property

Find

Time Aspect

Pt

System

Tiss

Scale Type

Doc

Method Type

Molgen

Details

Class

MOLPATH.PHARMG

Order/Observation

Both

Short Name

NTRK1+NTRK2+NTRK3 rearr Tiss

Display Name

NTRK1, NTRK2 and NTRK3 gene rearrangements Molgen Doc (Tiss)

Related Names

DocumentFindingFindingsMolecular geneticsMolecular pathologyMOLPATHMOLPATH.PHARMGNTRK1+NTRK2+NTRK3NTRK1+NTRK2+NTRK3 rearrPCRPoint in timeRandomRearrRearrangementTissueTissue, unspecified

Frequently Asked Questions

What is LOINC code 93813-4?

LOINC code 93813-4 identifies "NTRK1, NTRK2 and NTRK3 gene rearrangements in Tissue by Molecular genetics method". This test detects fusions (rearrangements) involving the NTRK1, NTRK2, and NTKR3 genes to identify solid tumors that may respond to NTRK-targeted therapies. These NTRK genes rearrange with more than 80 fusion gene partners, leading to tumorigenesis across a variety of tumor types.[PMID: 31075511] The collection of information contained by this term may include the test method(s), targeted fusion variants, the overall result (fusion variant detected/not detected), the fusion variant identified, the interpretation, recommendations, references and clinical trial information.

What does 93813-4 measure?

This code measures NTRK1 gene & NTRK2 gene & NTRK3 gene rearrangements in Tiss. It belongs to the MOLPATH.PHARMG class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.