93690-6
LaboratoryBRAF gene V600 mutations [Identifier] in Plasma cell-free DNA by Molecular genetics method Nominal
Definition
Detection of BRAF V600 variants, including V600E (Val600Glu, c.1799T>A) and V600K (Val600Lys, c.1798_1799delGTinsAA), in cell-free DNA. Using cell-free DNA is alternative to invasive tissue biopsies. The most prevalent mutations are V600E (70−90%) and V600K (5−30%); other mutations are rare. A positive result indicates the presence of an activating BRAF mutation and may be useful for guiding the treatment of individuals with melanoma.
LOINC 6-Axis Classification
Component
BRAF gene.p.Val600 mutations
Property
Prid
Time Aspect
Pt
System
Plas.cfDNA
Scale Type
Nom
Method Type
Molgen
Details
Class
MOLPATH.MUT
Order/Observation
Both
Short Name
BRAF p.V600 mutations Plas.cfDNA
Display Name
BRAF gene V600 mutations Molgen Nom (cfDNA)
Related Names
Frequently Asked Questions
What is LOINC code 93690-6?
LOINC code 93690-6 identifies "BRAF gene V600 mutations [Identifier] in Plasma cell-free DNA by Molecular genetics method Nominal". Detection of BRAF V600 variants, including V600E (Val600Glu, c.1799T>A) and V600K (Val600Lys, c.1798_1799delGTinsAA), in cell-free DNA. Using cell-free DNA is alternative to invasive tissue biopsies. The most prevalent mutations are V600E (70−90%) and V600K (5−30%); other mutations are rare. A positive result indicates the presence of an activating BRAF mutation and may be useful for guiding the treatment of individuals with melanoma.
What does 93690-6 measure?
This code measures BRAF gene.p.Val600 mutations in Plas.cfDNA. It belongs to the MOLPATH.MUT class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.