93480-2
LaboratoryCortisol post CRH stimulation panel - Serum or Plasma
Definition
The corticotropin releasing hormone (CRH) stimulation test is used to evaluate the hypothalamic-pituitary axis and help diagnose adrenocorticotrophic hormone (ACTH or corticotropin) dependent Cushing's disease. CRH stimulation cannot distinguish between Cushing's and pseudo-Cushing's. During this procedure, baseline cortisol measurements are taken followed by administration of 1 ug/kg of CRH, after which cortisol is measured again at timed intervals. In patients with Cushing's, cortisol concentrations at 30 and 45 minutes post CRH administration should be at least 20% higher than the mean baseline value.[NCBI Books: NBK278940] The timing for baseline and post-CRH cortisol measurements vary depending on local protocol. ACTH levels may also be measured [LOINC: 91707-0] as part of a CRH stimulation test.
LOINC 6-Axis Classification
Component
Cortisol post corticotropin releasing hormone stimulation panel
Property
-
Time Aspect
Pt
System
Ser/Plas
Scale Type
Qn
Method Type
N/A
Details
Class
PANEL.CHAL
Order/Observation
Order
Short Name
Cortisol p CRH stimulation Pnl SerPl
Display Name
Cortisol post CRH stimulation panel
Related Names
Frequently Asked Questions
What is LOINC code 93480-2?
LOINC code 93480-2 identifies "Cortisol post CRH stimulation panel - Serum or Plasma". The corticotropin releasing hormone (CRH) stimulation test is used to evaluate the hypothalamic-pituitary axis and help diagnose adrenocorticotrophic hormone (ACTH or corticotropin) dependent Cushing's disease. CRH stimulation cannot distinguish between Cushing's and pseudo-Cushing's. During this procedure, baseline cortisol measurements are taken followed by administration of 1 ug/kg of CRH, after which cortisol is measured again at timed intervals. In patients with Cushing's, cortisol concentrations at 30 and 45 minutes post CRH administration should be at least 20% higher than the mean baseline value.[NCBI Books: NBK278940] The timing for baseline and post-CRH cortisol measurements vary depending on local protocol. ACTH levels may also be measured [LOINC: 91707-0] as part of a CRH stimulation test.
What does 93480-2 measure?
This code measures Cortisol post corticotropin releasing hormone stimulation panel in Ser/Plas. It belongs to the PANEL.CHAL class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.