93450-5
LaboratoryCoagulation factor VIII inhibitor [Units/volume] in Platelet poor plasma by Chromogenic method
Definition
This term is created for but not restricted in use to a Nijmegen modification of the classic Bethesda inhibitor titration assay using a chromogenic method. The use of a chromogenic method allows factor VIII inhibitor to be detected in patients receiving emicizumab / Hemlibra®, a therapeutic that interferes with standard clot-based methods [PMID:29446525].
LOINC 6-Axis Classification
Component
Coagulation factor VIII Inhibitor
Property
ACnc
Time Aspect
Pt
System
PPP
Scale Type
Qn
Method Type
Chromo
Details
Class
COAG
Order/Observation
Both
Short Name
Fact VIII Inhib PPP Chro-aCnc
Display Name
Coagulation factor VIII inhibitor Chromogenic method Qn (PPP)
Related Names
Frequently Asked Questions
What is LOINC code 93450-5?
LOINC code 93450-5 identifies "Coagulation factor VIII inhibitor [Units/volume] in Platelet poor plasma by Chromogenic method". This term is created for but not restricted in use to a Nijmegen modification of the classic Bethesda inhibitor titration assay using a chromogenic method. The use of a chromogenic method allows factor VIII inhibitor to be detected in patients receiving emicizumab / Hemlibra®, a therapeutic that interferes with standard clot-based methods [PMID:29446525].
What does 93450-5 measure?
This code measures Coagulation factor VIII Inhibitor in PPP. It belongs to the COAG class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.