AutoICD API

92844-0

Laboratory

FLT3 gene internal tandem duplication/Normal [Ratio] in Blood or Tissue by Molecular genetics method

Definition

This term represents a ratio (allelic ratio), following PCR amplification, of a patient's FLT3 gene DNA having internal tandem duplication to that same patient's wild type FLT3 gene DNA not having such duplication. The result is expressed as a signal ratio of peak band intensities and correlates to cells with and without mutated DNA. A ratio of 100.00 is the maximum and indicates a patient specimen has 100% FLT3-mutated tumor with no healthy cells. A ratio between 0.03 and 0.05 indicates low levels of disease.

LOINC 6-Axis Classification

Component

FLT3 gene internal tandem duplication/normal

Property

Ratio

Time Aspect

Pt

System

Bld/Tiss

Scale Type

Qn

Method Type

Molgen

Details

Class

MOLPATH.MUT

Order/Observation

Both

Short Name

FLT3 ITD Dp/Nor Bld/T-Rto

Display Name

FLT3 gene internal tandem dup/Normal Molgen (Bld/Tiss) [Ratio]

Related Names

AmplificationBloodCD135ControlDpFL cytokine receptor precursorFLK2FLK-2FLT3 ITDfms-like tyrosine kinase 3fms-related tyrosine kinase 3Molecular geneticsMolecular pathologyMOLPATHMOLPATH.MUTATIONSPCRPoint in timeQNTQuanQuantQuantitativeRandomRatiosRtoStem cell tyrosine kinase 1STK1STK-1TissueTissue, unspecifiedWBWhole bloodWhole blood or Tissue

Frequently Asked Questions

What is LOINC code 92844-0?

LOINC code 92844-0 identifies "FLT3 gene internal tandem duplication/Normal [Ratio] in Blood or Tissue by Molecular genetics method". This term represents a ratio (allelic ratio), following PCR amplification, of a patient's FLT3 gene DNA having internal tandem duplication to that same patient's wild type FLT3 gene DNA not having such duplication. The result is expressed as a signal ratio of peak band intensities and correlates to cells with and without mutated DNA. A ratio of 100.00 is the maximum and indicates a patient specimen has 100% FLT3-mutated tumor with no healthy cells. A ratio between 0.03 and 0.05 indicates low levels of disease.

What does 92844-0 measure?

This code measures FLT3 gene internal tandem duplication/normal in Bld/Tiss. It belongs to the MOLPATH.MUT class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.