89041-8

LOINC code 89041-8 identifies "Lung cancer antibody [Interpretation] in Serum or Plasma by Immunoassay". Screening for lung cancer using computerized tomography (CT) has been shown to decrease mortality by 20%. CT is an expensive procedure that also can reveal non-malignant changes on the chest CT. The EarlyCDT-Lung assay is a cheaper alternative with fairly good sensitivity and specificity for detecting early, asymptomatic non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). To achieve the desired specificity of 90%, the autoantibody cutoff values were chosen based on that goal. The overall sensitivity/specificity of the assay was determined to be 38%/88%. When the sensitivity and specificity were measured based on the type of tumor, NSCLC was 34%/88% and SCLC was 50%/88%.[http://cancerpreventionresearch.aacrjournals.org/content/4/7/1126.long#ref-1]

This code measures Lung cancer antibody in Ser/Plas. It belongs to the SERO class in the LOINC classification.

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.