88056-7
LaboratoryAquaporin 4 water channel IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence
Definition
In vivo, IgG antibodies against aquaporin-4 (AQP4) cause fluorescence of small cerebral vessels, the pia and subpia, and the Virchow-Robin space on the optic nerve and cerebellar tissue. In vitro, cells transfected with AQP4 show smooth cytoplasmic fluorescence in the presence of AQP4 IgG antibodies with little fluorescence of the nucleus. This term was created for, but is not limited in use to, the Euroimmun NMO-IgG/aquaporin-4 immunofluorescence assay.
LOINC 6-Axis Classification
Component
Aquaporin 4 water channel Ab.IgG
Property
Titr
Time Aspect
Pt
System
CSF
Scale Type
SemiQn
Method Type
IF
Details
Class
SERO
Order/Observation
Both
Short Name
AQP4 H2O channel IgG Titr CSF IF
Display Name
Aquaporin 4 water channel IgG IF (CSF) [Titer]
Related Names
Frequently Asked Questions
What is LOINC code 88056-7?
LOINC code 88056-7 identifies "Aquaporin 4 water channel IgG Ab [Titer] in Cerebral spinal fluid by Immunofluorescence". In vivo, IgG antibodies against aquaporin-4 (AQP4) cause fluorescence of small cerebral vessels, the pia and subpia, and the Virchow-Robin space on the optic nerve and cerebellar tissue. In vitro, cells transfected with AQP4 show smooth cytoplasmic fluorescence in the presence of AQP4 IgG antibodies with little fluorescence of the nucleus. This term was created for, but is not limited in use to, the Euroimmun NMO-IgG/aquaporin-4 immunofluorescence assay.
What does 88056-7 measure?
This code measures Aquaporin 4 water channel Ab.IgG in CSF. It belongs to the SERO class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.