AutoICD API

87543-5

Laboratory

Beta-N-acetylhexosaminidase.A and beta-N-acetylhexosaminidase with reflex to HEXA gene panel [Enzymatic activity/mass] - Leukocytes

Definition

This panel contains quantitative results for beta-hexosaminidase A (HEX A) and total beta-hexosaminidase enzymatic activity in white blood cells (leukocytes) for the carrier detection and diagnosis of Tay-Sachs disease. This test may also be ordered for carrier detection and diagnosis of Sandhoff disease, but not all positive results indicate true carriers of Sandhoff disease so follow-up molecular testing is recommended.

LOINC 6-Axis Classification

Component

Beta-N-acetylhexosaminidase.A & beta-N-acetylhexosaminidase with reflex to HEXA gene panel

Property

CCnt

Time Aspect

Pt

System

WBC

Scale Type

-

Method Type

N/A

Details

Class

PANEL.CHEM

Order/Observation

Order

Short Name

Hex A & Total w Rflx HEXA Pnl WBC-cCnt

Display Name

Beta-N-acetylhexosaminidase.A and beta-N-acetylhexosaminidase with reflex to HEXA gene panel (WBC) [Catalytic activity/Mass]

Related Names

BBeta-hexosaminidase subunit alphabeta-N-acetylhexosaminidase geneB-NAHCatalytic ContentChemistryGM2 GangliosidosesGM2-gangliosidosisHex AHex A & Total w Rflx HEXA PnlHex BHEXAHexosaminidaseHexosaminidase Ahexosaminidase A (alpha polypeptide)hexosaminidase A (alpha polypeptide) geneLeukocytesN-acetyl-beta-glucosaminidase genePanPANEL.CHEMISTRYPanlPnlPoint in timeRandomSandhoff diseaseTay Sachs DiseaseTay-Sachs diseaseTSDWBCsWhite blood cells

Frequently Asked Questions

What is LOINC code 87543-5?

LOINC code 87543-5 identifies "Beta-N-acetylhexosaminidase.A and beta-N-acetylhexosaminidase with reflex to HEXA gene panel [Enzymatic activity/mass] - Leukocytes". This panel contains quantitative results for beta-hexosaminidase A (HEX A) and total beta-hexosaminidase enzymatic activity in white blood cells (leukocytes) for the carrier detection and diagnosis of Tay-Sachs disease. This test may also be ordered for carrier detection and diagnosis of Sandhoff disease, but not all positive results indicate true carriers of Sandhoff disease so follow-up molecular testing is recommended.

What does 87543-5 measure?

This code measures Beta-N-acetylhexosaminidase.A & beta-N-acetylhexosaminidase with reflex to HEXA gene panel in WBC. It belongs to the PANEL.CHEM class in the LOINC classification.

What is LOINC?

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.