86930-5
LaboratoryCarbapenemase [Presence] in Isolate
Definition
The detection of carbapenemase-producing isolates by various phenotypic methods, including the Modified Hodge Test (MHT) and Carbapemenase Inactivation Method (CIM). In MHT, carbapenemase production is detected when the test isolate produces the enzyme and allows growth of a carbapenem susceptible strain (E.coli ATCC 25922) towards a carbapenem disk. The result is a characteristic cloverleaf-like indentation. For CIM, a disk containing the indicator antibiotic meropenem is incubated for 2 hours in a bacterial suspension of the isolate. When the isolate produces carbapenemase, the meropenem in the disk is inactivated allowing uninhibited growth of an indicator strain.[PMID: 28476242]
LOINC 6-Axis Classification
Component
Carbapenemase
Property
PrThr
Time Aspect
Pt
System
Isolate
Scale Type
Ord
Method Type
N/A
Details
Class
MICRO
Order/Observation
Both
Short Name
Carbapenemase Islt Ql
Display Name
Carbapenemase Ql (Isol)
Related Names
Frequently Asked Questions
What is LOINC code 86930-5?
LOINC code 86930-5 identifies "Carbapenemase [Presence] in Isolate". The detection of carbapenemase-producing isolates by various phenotypic methods, including the Modified Hodge Test (MHT) and Carbapemenase Inactivation Method (CIM). In MHT, carbapenemase production is detected when the test isolate produces the enzyme and allows growth of a carbapenem susceptible strain (E.coli ATCC 25922) towards a carbapenem disk. The result is a characteristic cloverleaf-like indentation. For CIM, a disk containing the indicator antibiotic meropenem is incubated for 2 hours in a bacterial suspension of the isolate. When the isolate produces carbapenemase, the meropenem in the disk is inactivated allowing uninhibited growth of an indicator strain.[PMID: 28476242]
What does 86930-5 measure?
This code measures Carbapenemase in Isolate. It belongs to the MICRO class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.