85383-8
LaboratoryEGFR gene c.2369C>T actual/normal in Plasma cell-free DNA by Molecular genetics method
Definition
The EGFR gene mutation c.2369C>T leads to a mutation that interferes with the treatment of patients with non-small cell lung cancer. The mutation is detected in the plasma as free floating cell-free DNA and is present in 50-60% of patients resistant to treatment with first and second generation tyrosine kinase inhibitors.
LOINC 6-Axis Classification
Component
EGFR gene.c.2369C>T actual/normal
Property
RelRto
Time Aspect
Pt
System
Plas.cfDNA
Scale Type
Qn
Method Type
Molgen
Details
Class
MOLPATH.MUT
Order/Observation
Both
Short Name
EGFR c.2369C>T Act/Nor Plas.cfDNA
Display Name
EGFR gene c.2369C>T actual/normal Molgen (cfDNA) [Relative ratio]
Related Names
Frequently Asked Questions
What is LOINC code 85383-8?
LOINC code 85383-8 identifies "EGFR gene c.2369C>T actual/normal in Plasma cell-free DNA by Molecular genetics method". The EGFR gene mutation c.2369C>T leads to a mutation that interferes with the treatment of patients with non-small cell lung cancer. The mutation is detected in the plasma as free floating cell-free DNA and is present in 50-60% of patients resistant to treatment with first and second generation tyrosine kinase inhibitors.
What does 85383-8 measure?
This code measures EGFR gene.c.2369C>T actual/normal in Plas.cfDNA. It belongs to the MOLPATH.MUT class in the LOINC classification.
What is LOINC?
LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.