85095-8

LOINC code 85095-8 identifies "D-3-phosphoglycerate dehydrogenase IgG Ab [Presence] in Serum by Line blot". The qualitative result for the detection of IgG antibodies to D-3-phosphoglycerate dehydrogenase (PGDH) antigens in serum or plasma for the diagnosis of autoimmune liver diseases, including autoimmune hepatitis and primary biliary cirrhosis. This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot).

This code measures D-3-phosphoglycerate dehydrogenase Ab.IgG in Ser. It belongs to the SERO class in the LOINC classification.

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.