85092-5

LOINC code 85092-5 identifies "Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot". This panel contains results for the presence of IgG autoantibodies in serum or plasma for the diagnosis of autoimmune liver diseases, including autoimmune hepatitis and primary biliary cirrhosis. This panel was created for, but not limited in use to, the submitter's test strip, a membrane strip pre-coated with the following antigens: AMA-M2, M2-3E, Sp100, PML, gp210, LKM-1, LC-1, SLA/LP, SS-A, Ro-52, Scl-70, CENP A, CENP B and PGDH. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.

This code measures Liver diseases autoimmune Ab.IgG panel in Ser/Plas. It belongs to the PANEL.SERO class in the LOINC classification.

LOINC (Logical Observation Identifiers Names and Codes) is a universal standard for identifying laboratory and clinical observations. It is maintained by the Regenstrief Institute and used worldwide for health data exchange.